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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 40 Issue 6
Jun.  2024
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Article Contents

Risk factors and predictive models for liver cancer after sustained virologic response in hepatitis C

DOI: 10.12449/JCH240629
Research funding:

Scientific Research Project of Beijing Youan Hospital, CCMU, 2022 (BJYAYY-YN2022-02)

More Information
  • Corresponding author: ZHANG Jing, drzhangjing@163.com (ORCID: 0000-0002-3082-8330)
  • Received Date: 2023-11-12
  • Accepted Date: 2023-12-01
  • Published Date: 2024-06-25
  • Hepatitis C is one of the main causes of liver cancer. With the application of direct-acting antiviral agents, more than 95% of patients can achieve the eradication of hepatitis C virus and obtain sustained virologic response (SVR). Effective antiviral therapy can change the natural course of hepatitis C and reduce the risk of liver cancer; however, some patients are still affected by age, sex, liver fibrosis, diabetes, hepatic steatosis, alcohol consumption, and genetic factors and become the high-risk population of liver cancer. Therefore, it is needed to further clarify and improve the identification and prediction of high-risk populations of liver cancer after SVR of hepatitis C. This article reviews the risk factors and predictive models for liver cancer after SVR in patients with hepatitis C, in order to provide a basis for identifying the high-risk population of liver cancer after SVR of hepatitis C in clinical practice.

     

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