Objective To observe the therapeutic efficacy of atorvastatin in the treatment of non-alcoholic fatty liver disease (NAFLD) in patients with type Ⅱ diabetes mellitus.Methods A total of 118 patients with type Ⅱ diabetes mellitus complicated by NAFLD, who visited the outpatient department of internal ...

Objective To determine the protein expression profiles of STAT3 and its activated form, p-STAT3, in hepatocellular carcinoma (HCC) and investigate the potential clinical significance.Methods The expressions of STAT3 and p-STAT3 were detected in 90 HCC tissues and patient-matched cancer-adjacent heal...

Objective To investigate the differential expression of DNA methyltransferase (DNMT) in hepatocellular carcinoma (HCC) .Methods DNMT mRNA expression was measured by fluorescence quantitative-PCR in specimens of cancerous tissues (n=44) and case-matched cirrhotic (n=35) and non-cancerous, non-cirrhot...

Objective To construct the lentiviral vector carrying miR-122 (Lv-miR122) and investigate the function of stably expressed miR-122 in hepatocellular carcinoma (HCC) cells.Methods Pre-miR-122 was cloned into lentiviral vector pLUNIG to obtain the Lv-miR122 that had stable expression of miR-122;Lv-miR...

Objective To observe the changes in blood glucose in patients with liver cirrhosis and investigate the relationship between glucose metabolism and hepatic encephalopathy (HE) .Methods Sixty patients with liver cirrhosis (cirrhosis group) and 30 patients without liver cirrhosis (control group) , who ...

Objective To investigate the relationship between changes in serum cytokine levels at 72 h after artificial liver therapy (plasma exchange, PE) and clinical prognosis in patients with liver failure.Methods Fifty-eight patients with liver failure, who received PE in Department of Infectious Diseases,...

Objective To clinically analyze the hepatobiliary disease caused by the liver fluke and to increase the knowledge of this disease and reduce misdiagnosis.Methods A retrospective analysis was performed on the clinical data of 22 patients who had a confirmed diagnosis of clonorchiasis after being admi...

Pancreatic fistula, a common complication after pancreaticojejunostomy, is a deadly disease with high fatality.Thus, early detection of this condition, as well as effective prevention and treatment, is essential.Gives a further review of the diagnostic criteria for pancreatic fistula, the risk facto...

Endoplasmic reticulum stress (ERS) is a pathological condition characterized by the homeostasis imbalance and physiological dysfunction of endoplasmic reticulum.It is summarized from existing articles and reports that the various factors that lead to physical dysfunction can cause ERS and unfolded p...

Microvascular invasion (MVI) is considered an important influential factor for postoperative recurrence and prognosis of hepatocellular carcinoma (HCC) .Little attention has been given to the treatment targeting MVI, and the preoperative identification of MVI remains an unsolved challenge.This paper...

With the development of nanotechnology, its application in medical fields has attracted increasing attention from medical workers.Reviews the application of nanotechnology in the diagnosis and treatment of liver diseases in recent years, and expounds the advantages of nanotechnology in clinical appl...