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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 9
Sep.  2012
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Article Contents

Current perspectives on antiviral therapy for hepatitis C-related cirrhosis

  • Published Date: 2012-09-20
  • The most effective and widely used treatment for patients with chronic hepatitis C virus (HCV) infection is anti-viral therapy with a combination of interferon (IFN) and ribavirin.However, the tolerability for these drugs is low in patients with cirrhosis.Many studies have shown that HCV-related cirrhosis patients who achieve sustained viral response (SVR) after anti-viral therapy have significantly slower progression of liver fibrosis and a lower rate of HCV recurrence after liver transplantation.Therefore, patients with HCV-related cirrhosis should be monitored carefully to recognize and resolve adverse side effects of anti-viral treatments in a timely manner and to predict success of transplantation with non-recurrence.

     

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