Value of liver imaging scan in diagnosing hepatic veno-occlusive disease caused by Sedum Aizoon

Objective To investigate the liver imaging characteristics of acute and subacute hepatic veno-occlusive disease (HVOD) .Methods Clinical data of 45 cases who developed HVOD were collected and the clinical manifestation, imaging examination, histological examination of liver puncture biopsy, and the outcomes of changes were reviewed.Results 28 cases showed panther-stripe or patching low echogenic area of liver by ultrasonography.Map-like density changes was noticed in liver CT scan in all patients;Uniform signal intensity (SI) of liver showed in liver MR scan was big shape of low SI on TW1, slightly high SI on TW2, and map-like inhomogeneous enhancement.The diagnostic coincidence rates of HVOD were 100% on CT and MRI, as 62.2% (28/45) on ultrasonography.The difference between them was of statistical significance (χ2=15.06, P<0.05) .Map-like density changes showed in the liver CT and MR scan of 21 cases which were made sure by histological examination of liver.Conclusion Liver CT and MRI scan had higher sensitivity and specificity than ultrasonography in the diagnosis of HVOD.HVOD can be diagnosed by liver CT and MRI scan instead of histological examination.