Objective To investigate the clinical therapeutic effect of artificial liver plasma exchange therapy in patients with severe hepatitis.Methods 80 patients with severe hepatitis were divided into treatment group and control group, the treatment group was treated with plasma exchange on the basis of synthetic internal comprehensive medical treatment, and the control group was treated with synthetic internal comprehensive medical treatment alone.clinical symptoms and signs, liver and kidney function, blood coagulation function index changes of the two groups were observed before and after the treatment, and prognosis was analyzed and clinical curative effect was evaluated.Results After plasma exchange treatment, clinical symptoms were improved at different degrees.Liver function, kidney function and prothrombin time of the treatment group were significantly improved, compared with the results before treatment (P<0.05 or P<0.01) , whereas in the control group after treatment, the indicators in addition to Alb were significantly different (P<0.05 or P<0.01) .The total effective rate of the treatment group was 65.0%, among which early treatment rate was 88.9%, compared with control group differences were significant (P<0.05) Conclusion Artificial liver plasma exchange is an effective means of treatment for severe hepatitis and it is better for early stage patients.
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