Alteration and significance of intestinal flora in patients with NASH

Yang LinHui; Cai Jun; Chen DongFeng

Issue 2

Feb. 2012

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Article Navigation > Journal of Clinical Hepatology > 2012 > 28(2): 124-126

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Alteration and significance of intestinal flora in patients with NASH

Published Date: 2012-02-20

Abstract

Abstract

Objective To investigate alteration and significance of intestinal flora in patients with NASH.Methods Intestinal bacteria were routinely cultured and counted.Thirty health adults, thirty patients with nonalcoholic fatty liver and thirty patients with nonalcoholic steatohepatitis were selected and their intestinal bacteria were detected respectively.Results Alteration of intestinal flora included decrease in anaerobic bacteria (P<0.05) and increase in aerobic bacteria (P<0.05) in patients with NASH.There was no significant change in aerotolerant anaerobe such as toruloid fungi (P>0.05) .Conclusion There is alteration in intestinal flora and overgrowth of gram negative bacilli in patients with NASH.The results suggest that unbalance of intestinal microecology probably involve in the development of NASH.
- intestinal flora,
- fatty liver disease

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References

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Alteration and significance of intestinal flora in patients with NASH

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