中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 12
Dec.  2011

HBV mother-to-child transmission block-agreement and controversy

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  • Received Date: 2011-07-22
  • Published Date: 2011-12-20
  • Hepatitis B virus (HBV) infection is one of the most severe public issue due to its serious harmful clinical outcomes such as cirrhosis or HCC.The mother-to-child transmission (MTCT, vertical transmission) is the main cause leading to chronic HBV infections.Though joint HBV immune prophylaxis with hepatitis B vaccine and hepatitis B immunoglobulin (HBIG) are given within 24hrs after birth for all neonates whose mothers are HBV positive, about 10% of them suffer from HBV infection in their early life, even in pregnant women with a high HBV DNA serum load.This paper discusses the thesis concerning on agreement and controversy regarding the MTCT.

     

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