Objective This study aims to investigate the clinical features of cirrhosis due to nonalcoholic steatohepatitis.Methods Clinical data of twenty patients diagnosed as cirrhosis due to nonalcoholic steatohepatitis was retrospectively analyzed and compared with thirty patients diagnosed as cirrhosis due to hepatitis B.The index including gender, age, blood sugar, blood fat, WBC, platelet, PTA%, INR, TBil, albumin, choline phospholipid, urea nitrogen, creatinine, electrolyte, AFP, abdomen ultrasound and gastroscopy report was recorded.MELD score was calculated.The difference of data between two groups was compared.Results The average age in the group of cirrhosis due to nonalcoholic steatohepatitis is (69.15±13.84) years, which is older than that in control group [ (48.67±15.09) years, P=0.021].Male accounts 35% (7/20) and female accounts 65% (13/20) , while in control group male accounts 80% (24/30) and female accounts 20% (6/30) .Morbidity of hypertension, diabetes and hyperlipemia is higher than that in control group (respectively 60%vs 16.7%, 75%vs 46.7%, 55%vs 10%, P=0.008, 0.015, 0.041) .PTA% is significantly higher than that in control group [ (75.26±8.57) % vs (52.37±10.86) %, P=0.038) ].INR was obviously lower than that in control group [ (1.03±0.25) vs (1.44±0.31) , P=0.042].Incidence of electrolyte disturbances was 5% (1/20) , which is significantly lower than that in control group 63.3% (19/30, P=0.023) .MELD score is obviously lower than that in control group [ (7.69±3.46) vs (16.54±9.50) , P=0.002].Conclusion The clinical features of cirrhosis due to nonalcoholic steatohepatitis were listed as following: (1) older age; (2) more common in female than male; (3) higher morbidity due to hypertension, diabetes and hyperlipemia; (4) better liver function and kidney function; (5) less such complications as electrolyte disturbances and hepatorenal syndrome; (6) better prognosis; (7) portal hypertension manifestations such as hypersplenism, EV and ascitis are similar to cirrhosis due to hepatitis B.
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