中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 2
Feb.  2011

Research in the progress of non-invasive diagnosis of liver fibrosis

  • Published Date: 2011-02-20
  • Liver fibrosis is a life-threatening disease evolving from different liver disease,is one of the most common cause of death.Fibrosis is characterized by excessive deposition of extracellular matrix in the tissue and tissue restatement as consequence of chronic liver damage.Liver biopsy is the most reliable indicator of the degree of hepatic fibrosis and inflammatory activity,but biopsy is an invasive examination.There are some risks and limitations,so it is necessary to look for an accurate and reliable non-invasive method to provide the basis for diagnosis and treatment of liver fibrosis.In recent years,advances in serology and imageology such as serum marker panels,FibroScan,et al can assess fibrosis accurately and reduce the need for a liver biopsy.But at present,all have failed to completely replace liver biopsy because of their respective limitations in current researches.The searching for an ideal surrogate is still in progress.

     

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