The incidence and prognosis of non-alcoholic fatty liver disease in primary liver cancer 1293 cases

Objective To analyze the clinical data of 1293 primary liver cancer cases and the NAFLD-related primary liver cancer in order to explore the prognosis of primary liver cancer caused by NAFLD retrospectively.Methods The data of primary liver cancer (PHC) cases were assessed and 75 cases of NAFLD were selected.The incidence of NAFLD-related liver cancer and the indicators that may affect the prognosis were analyzed.Results From the 75 NAFLD cases of 5.8% were with PHC and 42 cases PHC with NAFLD died during the follow-up.The overall 1, 2, and 3-year survival rates were 60.55%, 38.63% and 29.53%, respectively.BMI, Type 2 Diabetes, ALT, TBil /DBil, GGT and CHE had an influence on the survival rate (P < 0.05) .BMI was the only independent prognostic factor (χ2 = 5.766, P = 0.016) .Conclusion NAFLD may induce PHC.Obesity and Type 2 Diabetes could be the risk prognostic factors of NAFLD-related hepatocellular carcinoma.Patients with high BMI have poor prognosis.