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Article Navigation >  Journal of Clinical Hepatology  > 2010  >  26(1): 44-46

The Specific Expression and Pathological Diagnostic Value of Survivin in Gallbladder Adenoma

  • Published Date: 2010-01-20
    Abstract
  • Objective To evaluate the relative production and the clinical value of survivin in pathological diagnosis of gallbladder adenoma by observing the site of expression and the characteristics of survivin, the apoptosis inhibitor.Methods The expression of survivin in gallbladder adenoma was detected from 25 samples by immunohistochemical method SP.Results From a total of 25 gallbladder adenoma specimens 23 were reactive to survivin, which expressed on the cytoblast in cytoplasm with cytoblast-like 17, bedload-like 4 and diffusing 2 expression.Conclusion Survivin expression location and its characteristics may have important clinical value in pathological diagnosis of gall bladder adenoma.

     

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    [6]Zaffaroni N, Pennati M, Daidone MG.Survivin as a target for new anticancer intervention[J].J Cell Mol Med, 2005, 9 (2) ∶360-372.
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    [8]Kazuhiro K, Ryuichiro D, Masayuki K, et al.Survivin expression is a prognostic marker in pancreatic cancer patients[J].Surgery, 2004, 13 (2) ∶443-448.
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