胆汁CEA、CA19-9联合检测对肝外胆管癌及壶腹癌的诊断价值

Objective To determine the valuable tumormarkers of CEA and CA19-9 in the bile for diagnosis of cholangiocarcinoma and carcinoma of ampulla.Methods Serum CEA and CA19-9 were detected by radio immunoassay in 38 patients of observation group with cholangiocarcinoma and carcinoma of ampulla before endoscopic retragrade cholangiopancreatography (ERCP) , took 5ml bile to detecte CEA and CA 19-9 While ERCP, and took endoscopic biopsy for histopathological with the help of wise, recorded the feature of imaging.Bile CEA and CA19-9 were detected in 30 patients with unmalignant of contrast group in the same way.Results There were significance in the bile level of CEA or CA 19-9 between the two groups (P<0.05) , it is coincide to the histopathological.There were significance in the level of CA 19-9 between the bile and the serum (P<0.05) , but no significance in the level of CEA (P>0.05) .Conclusion The tumormarkers of CEA and CA19-9 in the bile for diagnosis of cholangiocarcinoma and carcinoma of ampulla have important valuable.