胰蛋白酶原激活肽与急性胰腺炎严重程度的相关性研究

Objective To investigate the correlation between TAP levels in plasma and urine and severity in patients with acute pancreatitis and their clinical significances.Methods the plasma and urinary TAP levels were measured with ELISA methods in 53 patients with acute pancreatitis (AP) and 30 normal subjects.Results the plasma and urinary TAP levels in AP patients were significantly higher than that in healthy people (P<0.01) .the plasma and urinary TAP levels in patients with severe acute pancreatitis were significantly higher than in those with mild acute pancreatitis (P<0.01) .Conclusion The plasma and urinary TAP levels are related to the development of acute pancreatitis, The measurement of plasma and urinary TAP may contribute to predict the severity of AP and guide clinical treatment.