Researeh on the correlation between the contents of serum HBV DNA and liver function and liver tissue injury in hepatitis B patients.

Liu LongGen; Zhai DeFang; Liu JianHong; Qian MeiYun; Fang GuoPing

Issue 1

Jan. 2005

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Article Navigation > Journal of Clinical Hepatology > 2005 > 21(1): 7-8

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乙型肝炎患者血清HBVDNA负荷与其肝功能及肝组织损害的关系研究

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Published Date: 2005-01-20

Abstract

Abstract

To evaluate the serum HBV DNA level in hepatitis B and its relation with liver function and liver tissue injury.380 untreated patients with hepatitis B were selected and their serum HBVDNA level and liver function were detected, and among them 71 cases received liver biopsy.Serum HBVDNA level disaccord with state of their illness;serum ALT and TBil in those HBVDNA (+) and HBVDNA (-) have no difference (P>0.05) ;HAI scores have no relation with serum HBVDNA level (P>0.05) .Serum HBVDNA level cannot reflect the state of hepatitis illness, and no correlation with inflammation and fibrosis in liver.
- Hepatitis B,
- HBVDNA,
- Liver function Liver tissue,

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[1]张玉琦, 周秀梅, 丁明权, 等.乙型肝炎患者血清HBVDNA水平与临床特征的关系[J].医学临床研究, 2003, 20 (9) ∶676-78.

[2]刘伟, 赵伟, 罗婵.慢性乙型肝炎得血清HBVDNA负荷与其肝组织炎症活动度相关性研究[J].临床肝胆病杂志, 2002, 18 (1) :26-27.

[3]陈然峰, 陈国军, 黄晓文, 等.HBVDNA的表达与肝纤维化的相关性研究[J].临床肝胆病杂志, 2002, 18 (6) ∶354-355.

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[5]随云华, 杨志国, 许家璋, 等.HBVDNA定量与乙型肝炎临床及病理的关系[J].现代诊断与治疗, 2002, 13 (5) ∶266-268.

[6]成军, 杨守成, 现代肝炎病毒分子生物学[M ].北京∶人民军医出版社, 1997∶30.

[7] ZavagliaC , MondaziiL , MaggiG , etal.Arealanineaminotrans-ferase, hepatitisBvirusDNAorIgMantibodytohepatitisBcoreanti genserumlevelspredictorsofhistologicalgradinginchronichepatitisB ?[J].Liver, 17∶83-87.

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沈阳化工大学材料科学与工程学院沈阳 110142

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乙型肝炎患者血清HBVDNA负荷与其肝功能及肝组织损害的关系研究

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乙型肝炎患者血清HBVDNA负荷与其肝功能及肝组织损害的关系研究

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