中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 6
Jun.  2004
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射频联合全身化疗治疗肝肿瘤的坏死范围及安全性

  • Published Date: 2004-06-20
  • To compare a short term efficacy and safety of radiofrequency combined with systemic chemotherapy with those of radiofrequency alone in patients with primary and secondary hepatic cancer. The study population consisted of 63 patients with primary or secondary hepatic cancer. Among these, 28 patients were treated with radiofrequency combined with systemic chemotherapy and the remaining 35 patients were treated with radiofrequency alone. All patients were followed up using contrast-enhanced computed tomography 1 month after treatment. There were significant differences in the necrosis range between radiofrequency combined with systemic chemotherapy and radiofrequency alone in larger hepatic cancer group. There were no significant differences in the target of safety in all groups. Radiofrequency is effective and safe in treating hepatic cancer. Radiofrequency combined with systemic chemotherapy could increase tumor destruction in treating larger hepatic cancer group compared with radiofrequency alone and this combination is relatively safe.

     

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  • [1] LencioniR , cioniD , DonatiF , etal.Combinationofinterventionalther apiesinhepatocellularcarcinoma[J].Hepatogastroenterology, 2001, 48 (37) ∶8-14.
    [2] GoldbergSN , GirnanGD , LukyanvoAN , etal.Percutaneoustumorab lation:increasednecrosiswithcombinedradio-frequencyablationandintravenousliposomaldoxorubicininaratbreasttumormode[J].Radiol ogy, 2002, 222 (3) ∶797-804.
    [3] BuscariniL , BuscariniE .TherapyofHCC -radiofrequencyablation.Hepatogastroenterology, 2001, 48 (37) ∶15-19.
    [4] GoldbergSN , KamelIR , KruskalJB , etal.Radiofrequencyablationofhepatictumors:increasedtumordestructionwithadjuvantliposomaldox orubicintherapy[J].AJRAmJRoentgenol, 2002, 179 (1) ∶93-101.
    [5] CurleySA .Radiofrequencyablationofmalignantlivertumors[J].Oncol ogist, 2001, 6 (1) ∶14-23.
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