中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 3
Mar.  2003

血清氨基酸指标在病毒性肝炎及肝炎肝硬化诊断中的意义

  • Published Date: 2003-03-20
  • Objective To Study the independent predictable ones in serum amino-acid analysis markers for acute viral hepatitis, chronic viral hepatitis and posthepatitis cirrhosis, and to find out the value of them.Methods 123 patients was composed of 22 cases with acute viral hepatitis, 59 cases with chronic viral hepatitis and 42 cases with liver cirrhosis.Serum amino-acid markers analysis was performed by chromatomertry, and statisticsed by stepwise discriminant analysis after transformed by logarithm. By stepwise discriminant analysis, serum taurine, leucine, tyrosine, urea and glycine were the independent agents among them.In addition, between the acute viral hepatitis and chronic viral hepatitis, and between chronic viral hepatitis and liver cirrhosis aspartic acid and threonine also have important value respectively.In the hepatopathy caused by hepatovirus infection, it's important for clinical diagnosis and determination liver function store to assay serum taurine, leucine, tyrosine, urea, glycine, et al, in amino-acid markers.

     

  • [1]Niromiya T, Yoon S, Sugano M, et al. Improvement of molar ratio of branched-chain amino acids to tyrosine (BTR) associated with liver fibrosis in chronic hepatitis C patients treated with interferon-alpha[J]. Dig Dis Sci, 1999, 44 (5) ∶1027-33.
    [2] Suzuki H, Mamata Y, Tominaga T, et al. Influence of alcohol on branched-chain amino acid/tyrosine molar ratio in patients with cirrhosis[J].Alcohol Clin Exp Res, 1998, 22 (3 Suppl) ∶ 137S-140S.
    [3]Marchesini G, Bianchi G, Brizi M, et al. Nutritional treatment with branched-chain amino acids in advanced liver cirrhosis[J]. J Gastroenterol, 2000, 35Suppl 12∶7-12.
    [4]Kawamura Yasui N, Kaito M, Fujita N, et al. Evaluating response to nutritional therapy using the branched-chain amiro acid/tyrosine ratio in patients with chronic liver disease[J]. J Clin Lab Anal, 1999, 13 (1) ∶31-4.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (3610) PDF downloads(947) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return