重型乙型肝炎血清β2-微球蛋白检测及临床意义

To study the relationship between the level of serum β 2-microglobulin and the degree of liver damage in patients with grave hepatitis B. Using radiation immune assay (RIA) to detect of serum β 2 -microglobulin in 53 patients with grave hepatitis, 44 patients with acute hepatitis and 31 contrasts. The level of serum β 2-microglobulin in patients with grave hepatitis is significantly higher than that in patients with acute hepatitis and contrasts, it also showed negative correlation with Alb, positive correlation with ALT, T-Bil and PT in patients with grave hepatitis. Meanwhile, it was significantly higher in patients died from grave hepatitis B than in survival of the same disease. Serum β 2-microglo bulin is a good index that reflects the degree of liver damage, and is important in realizing the state and prognosis of the patients with grave hepatitis B.