中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 2
Feb.  2000

泰特对肝硬化患者抗氧化能力影响的评价

  • Published Date: 2000-02-20
  • WT5”BZ] Objective:To value the effect of TAD to the ability of antioxidant with the cirrhosis Sixty patients with cirrhosis were respectively treated with TAD and inesine The measure of the glutathione (GSH) and malonaldehyde (MDA) in the erythrocyte was made after 2 weeks Results:The content of GSH in patients erythrocyte was lower than that in normal erythrocyte (204 72±28 09) g/l and (334 10±5 00) g/l;the lever of MDA in the patients erythrocyte was higher than that in normal erythrocyte (10 38±1 69) nmol/ml and (6 38±0 07) nmol/ml;After treatment, the content of the GSH increased (297 10±19 99) g/L and (230 43±51 8) g/L and that of MDA decreased (8 63±2 01) nmol/ml and (9 27±1 49) nmol/ml There is significantly difference in the lever of GSH between the two treatments with TAD and with Inosine (P<0 01) but there is no difference in MDA between two treatments conclusion:The ability of antioxidant is lower in cirrhosis patients and TAD can improve the ability of antioxidant [WT5”HZ]

     

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    [2 ]LewisK O PotonA CouldSuperoxidaCauseCirrhosis Lancet, 1982 , 2∶188
    [3 ]RobertoCorrcher , M Casaril, G Bellisoal, G B Gabrielli, N Nicol i, G CGuidi Severeimpairmentofantioxidantsysteminhumanhepectoma Cancer , 1986, 5 8∶165 8
    [4] 袁爱力 , 罗元辉 , 梁后杰 肝癌及肝硬化时脂质过氧化作用的临床及实验研究 中华内科杂志 , 1991, 3 0 ( 6) ∶3 63
    [5 ]黄诚承 , 吴孟超 原发性肝癌患者脂质过氧化物的研究 中华消化杂志 , 1992 , 12 ( 2 ) ∶12 0
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