Research advances in brain lactate level and hepatic encephalopathy

Yuqin LIU; Mi CHEN; Lanyan TANG; Lizhi ZHOU; Xin HUANG; Pan ZHANG

doi:10.3969/j.issn.1001-5256.2023.07.031

Volume 39 Issue 7

Jul. 2023

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Article Navigation > Journal of Clinical Hepatology > 2023 > 39(7): 1728-1733

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Research advances in brain lactate level and hepatic encephalopathy

DOI: 10.3969/j.issn.1001-5256.2023.07.031

Department of Infectious Diseases, The Third Xiangya Hospital of Central South University, Changsha 410000, China

Research funding:

Natural Science Foundation of Hunan Province (2020JJ4862)

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Corresponding author: ZHANG Pan, zhangp2017@163.com (ORCID: 0000-0001-8778-4079)
Received Date: 2022-09-25
Accepted Date: 2022-11-14
Published Date: 2023-07-20

Abstract

Abstract

Hepatic encephalopathy (HE) is a common complication and an independent risk factor for death in patients with liver cirrhosis. Brain lactate level is associated with the progression and severity of HE, and research on brain lactate level may help to further explain the pathogenesis of HE. This article summarizes the metabolic process of brain lactate, the association between brain lactate level and HE, and the potential therapeutic targets for HE and provides a reference for clinicians to further systematically evaluate the progression, treatment outcome, and prognosis of patients with HE, in order to reduce the medical burden of patients and improve the prognosis of patients with HE.
- Hepatic Encephalopathy,
- Lactic Acid,
- Blood-Brain Barrier,
- Brain Edema

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References

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Research advances in brain lactate level and hepatic encephalopathy

DOI: 10.3969/j.issn.1001-5256.2023.07.031

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Research advances in brain lactate level and hepatic encephalopathy

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