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CN 22-1108/R
Volume 39 Issue 6
Jun.  2023
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Article Navigation >  Journal of Clinical Hepatology  > 2023  >  39(6): 1446-1453

Research advances in nonalcoholic fatty liver disease in individuals with HIV infection

DOI: 10.3969/j.issn.1001-5256.2023.06.030

  • Qinghai Province Key Laboratory of Hydatid Disease Research, Department of Hepatobiliary and Pancreatic Surgery, The Affiliated Hospital of Qinghai University, Xining 810001, China

Research funding:

2021 Qinghai Province “Kunlun Talents· High － end Innovative and Entrepreneurial Talents” 

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  • Corresponding author: REN Bin, renbing51@aliyun.com (ORCID: 0000-0002-9742-4082)
  • Received Date: 2022-11-20
  • Accepted Date: 2023-01-02
  • Published Date: 2023-06-20
    Abstract

  • The prevalence rate of nonalcoholic fatty liver disease (NAFLD) tends to increase in the general population around the world, and the incidence rate of liver malignancies caused by NAFLD is also increasing continuously. Obesity is an independent risk factor for NAFLD. Among the individuals with HIV infection who have a normal body weight, 25% have NAFLD, and lean NAFLD is relatively common in individuals with HIV infection. With reference to related articles in China and globally, this article reviews the epidemiology, pathophysiology, histology, diagnosis, screening, intervention, treatment, and clinical management of NAFLD, in order to improve the awareness of NAFLD in individuals with HIV infection among the public, clinicians, and related institutions.

     

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