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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 35 Issue 10
Oct.  2019
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Article Contents

Clinical significance and application of quantification of hepatitis B core antibody

DOI: 10.3969/j.issn.1001-5256.2019.10.005
  • Received Date: 2019-08-09
  • Published Date: 2019-10-20
  • Hepatitis B virus(HBV) infection is a global public health problem. Hepatitis B core antibody(anti-HBc) is one of the serum immunological markers in human body after HBV infection. Previous studies have shown that the low serum level of anti-HBc in HBeAg-positive mothers are associated with immunoprophylaxis failure in infants. In addition,anti-HBc is an important biomarker associated with liver inflammatory activity and therapeutic outcome and can be used to evaluate liver inflammation and predict the efficacy of antiviral therapy and sustained response after drug withdrawal. Anti-HBc quantification provides a new direction for individualized treatment of hepatitis B patients.

     

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