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Volume 41 Issue 8
Aug.  2025
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Article Navigation >  Journal of Clinical Hepatology  > 2025  >  41(8): 1679-1684

Research advances in the impact of reduction in portal venous pressure after transjugular intrahepatic portosystemic shunt on prognosis

DOI: 10.12449/JCH250832

  • Department of Gastroenterology，The Second Affiliated Hospital of Kunming Medical University，Kunming 650000，China

Research funding:

Yunnan Province “Ten Thousand Talents Plan” Special Medical Talent Initiative (YNWR-MY-2019-074)

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  • Corresponding author: ZHAO Gongfang， zhaogongfangedu@163.com （ORCID： 0000-0001-9178-1567）
  • Received Date: 2024-11-24
  • Accepted Date: 2025-01-20
  • Published Date: 2025-08-25
    Abstract
  • Transjugular intrahepatic portosystemic shunt （TIPS） is an important intervention for portal hypertension， and the degree of reduction in portal venous pressure is closely associated with the prognosis of patients. While a greater reduction in portal venous pressure may lead to more effective alleviation of portal hypertensive symptoms in cirrhotic patients， it also increases the risk of hepatic encephalopathy and liver failure. Therefore， appropriate control of the degree of reduction in portal venous pressure is essential for optimizing therapeutic outcomes. This article reviews the methods for measuring portal venous pressure， the factors affecting the reduction in portal venous pressure， the optimal range for reduction in different indications， and the impact of varying degrees of pressure reduction on complications， in order to provide guidance for improving the treatment outcome of TIPS and the prognosis of patients after surgery.

     

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