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ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 40 Issue 11
Nov.  2024
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Article Navigation >  Journal of Clinical Hepatology  > 2024  >  40(11): 2173-2176

Unified consensus and evolution of the definition of acute-on-chronic liver failure： Seeking common ground while reserving differences

DOI: 10.12449/JCH241108

  • Fourth Department of Liver Disease Center，Beijing YouAn Hospital，Capital Medical University，Beijing 100069，China

Research funding:

Construction Project of High-level Technology Talents in Public Health (Discipline Leader-01-12);

Beijing Hospitals Authority’s Ascent Plan (DFL20221501)

  • Received Date: 2024-10-01
  • Accepted Date: 2024-10-20
  • Published Date: 2024-11-25
    Abstract
  • The concept of acute-on-chronic liver failure （ACLF） has been introduced for nearly 30 years， and with extensive research on its pathogenesis， diagnostic criteria， and treatment strategies， related consensus statements and guidelines have been constantly updated in China and globally； however， there is still a lack of a unified definition of ACLF， and such differences in definition may inevitably hinder the application and implementation of various treatment methods， prognostic scoring systems， and clinical recommendations. In recent years， hepatology experts have continuously proposed methods to unify the definition of ACLF， seeking common ground while reserving differences and drawing on the strengths of various definitions， in order to achieve a more unified definition of ACLF.

     

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