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Volume 40 Issue 9
Sep.  2024
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Article Navigation >  Journal of Clinical Hepatology  > 2024  >  40(9): 1886-1890

Role of inflammatory cytokines in disorder of glucose metabolism in patients with liver cirrhosis

DOI: 10.12449/JCH240926

  • Department of Infectious Diseases，Affiliated Hospital of Zunyi Medical University，Zunyi，Guizhou 563000，China

Research funding:

National Natural Science Foundation of China (81860114)

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  • Corresponding author: LIN Shide， linshide6@zmc.edu.cn （ORCID： 0000-0001-8803-4069）
  • Received Date: 2023-12-13
  • Accepted Date: 2024-02-22
  • Published Date: 2024-09-25
    Abstract
  • In recent years， there has been a deeper understanding of the role and mechanisms of common inflammatory cytokines in the development and progression of liver cirrhosis， such as interleukin-1β， interleukin-6， interleukin-10， interleukin-17， tumor necrosis factor-α， interferon-γ， and C-reactive protein， and significant achievements have also been made in the research on the association of these inflammatory cytokines with disorder of glucose metabolism and pancreatic islet dysfunction. This article reviews the role of inflammatory cytokines in patients with liver cirrhosis and their impact on disorder of glucose metabolism and pancreatic islet dysfunction， in order to provide a theoretical basis for clarifying the pathogenesis of hepatogenous diabetes and performing the clinical management of the disease.

     

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