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ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 40 Issue 4
Apr.  2024
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Article Navigation >  Journal of Clinical Hepatology  > 2024  >  40(4): 804-809

Mechanism of action of traditional Chinese medicine in treatment of nonalcoholic fatty liver disease based on intestinal microecology

DOI: 10.12449/JCH240426
  • 1.

    School of Acupuncture and Massage，Shandong University of Traditional Chinese Medicine，Jinan 250014，China

  • 2.

    Preventive Treatment Center，The Affiliated Hospital of Shandong University of Traditional Chinese Medicine，Jinan 250014，China

Research funding:

Key Discipline of Shandong University of Traditional Chinese Medicine： Traditional Chinese Medicine Prevention and Treatment ;

Chaoyang Talent Project of Shandong University of Traditional Chinese Medicine Affiliated Hospital 

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  • Corresponding author: YU Huijuan， huijuanyu@163.com （ORCID： 0000-0003-1180-5704）
  • Received Date: 2023-09-02
  • Accepted Date: 2023-09-18
  • Published Date: 2024-04-25
    Abstract
  • Nonalcoholic fatty liver disease （NAFLD） is a multisystem disease associated with obesity， insulin resistance， and dyslipidemia and has a complex pathogenesis. Studies have shown that gut microbiota dysbiosis is closely associated with the onset of NAFLD， and traditional Chinese medicine treatment can improve the laboratory markers and clinical symptoms of NAFLD patients by regulating intestinal microbiota and its metabolites. This article elaborates on the association between NAFLD and gut microbiota， the involvement of gut microbiota dysbiosis in the pathogenesis of NAFLD， and the possible mechanism of traditional Chinese medicine treatment in improving NAFLD from the perspective of gut microbiota， in order to provide new ideas for the treatment of NAFLD.

     

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    The first journal specializing in hepatobiliary and pancreatic diseases in China

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