Portal vein thrombosis in liver cirrhosis： Risk factors and protection strategies

Wenjuan FENG; Ning ZHOU; Yulu WANG; Zhaoqin BAI

doi:10.12449/JCH240128

Volume 40 Issue 1

Jan. 2024

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Article Navigation > Journal of Clinical Hepatology > 2024 > 40(1): 169-174

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Portal vein thrombosis in liver cirrhosis： Risk factors and protection strategies

DOI: 10.12449/JCH240128

Wenjuan FENG¹,
Ning ZHOU^{1, 2
,
,
,},
Yulu WANG¹,
Zhaoqin BAI^{1, 2}

1.
Gansu University of Chinese Medicine，Lanzhou 730000，China
2.
Department of Gastroenterology，Lanzhou First People’s Hospital，Lanzhou 730050，China

Research funding:

Key Research and Development Project of Science and Technology Department of Gansu Province (21YF5FA169);

Lanzhou Talent Innovation and Entrepreneurship Project (2021-RC-107)

More Information

Corresponding author: ZHOU Ning， zhouning198278@163.com （ORCID： 0000-0001-8988-2860）
Received Date: 2023-04-27
Accepted Date: 2023-05-23
Published Date: 2024-01-23

Abstract

Abstract

Portal vein thrombosis （PVT） is one of the common complications during the natural course of liver cirrhosis and has an important influence on the progression of liver cirrhosis. This article mainly summarizes the research advances in the risk factors for PVT. There are many risk factors for PVT， and Virchow’s triad， namely venous stasis， hypercoagulability， and vascular endothelial injury and systemic inflammation caused by surgery or trauma， are considered the main reasons for the development and progression of PVT. At present， more prospective studies are still needed to validate the predictive models for the risk of PVT that have certain application prospects in clinical practice. Cirrhotic patients with PVT tend to have a poor prognosis， and complete obstructive PVT is associated with increased mortality after liver transplantation. Recent studies have shown that prophylactic anticoagulant therapy is safe and effective in patients with liver cirrhosis and can thus help with the prevention and treatment of PVT.
- Liver Cirrhosis,
- Portal Vein,
- Venous Thrombosis

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References(59)

References

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Portal vein thrombosis in liver cirrhosis： Risk factors and protection strategies

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Portal vein thrombosis in liver cirrhosis： Risk factors and protection strategies

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