2019 No. 7

2019 Vol. 35, No. 7

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Editorial

Diagnosis and treatment of chronic hepatitis B in women of child-bearing age and strategies for blocking mother-to-child transmission

Han GuoRong

2019, 35(7): 1417-1420. DOI: 10.3969/j.issn.1001-5256.2019.07.001

Abstract(1467)

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Abstract:
Women with chronic hepatitis B virus ( HBV) infection face both maternal and child problems during pregnancy. One problem is to prevent hepatitis activities during pregnancy, and the other is to block mother-to-child transmission. Infants born to HBeAg-positive mothers may have a rate of chronic HBV...

Discussions by experts

Influence of chronic HBV infection on maternal and neonatal outcomes of women with gestational diabetes mellitus

Xu ChuanLu, Ying Hao

2019, 35(7): 1421-1424. DOI: 10.3969/j.issn.1001-5256.2019.07.002

Abstract(1475)

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Abstract:
There are relatively few studies on the association between chronic hepatitis B virus ( HBV) infection during pregnancy and gestational diabetes mellitus ( GDM) , with inconsistent conclusions. A meta-analysis of 23 cohort studies conducted in 2018 showed that HBs Ag-positive pregnant women had a hi...

Influence of hepatitis B virus infection on assisted reproductive technology and related prevention measures

Zhu Tong, Li ChengZhong

2019, 35(7): 1425-1429. DOI: 10.3969/j.issn.1001-5256.2019.07.003

Abstract(1364)

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Abstract:
Hepatitis B virus ( HBV) infection is prevalent in China. With the rapid development of assisted reproductive technology ( ART) in recent years, more and more couples with infertility and HBV infection choose ART to promote pregnancy. No conclusion has been reached on the influence of HBV infection ...

Influence of pregnancy on the natural history of chronic hepatitis B virus infection

Chen YuXin, Huang Rui, Wu Chao

2019, 35(7): 1430-1434. DOI: 10.3969/j.issn.1001-5256.2019.07.004

Abstract(1592)

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Abstract:
Chronic hepatitis B virus ( HBV) infection is still a serious public health problem in China, and the HBsAg carrying rate reaches6. 0%-7. 8% in pregnant women. Maternal immune system is suppressed during pregnancy, which may affect the natural history of HBV infection. At present, no consensus has b...

Early diagnosis of liver disease during pregnancy should be taken seriously

Zheng YiShan

2019, 35(7): 1435-1438. DOI: 10.3969/j.issn.1001-5256.2019.07.005

Abstract(1418)

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Abstract:
Adaptive physiological changes during pregnancy lead to increased fragility of the liver, impaired buffer capacity, and rapid disease progression, and such changes may weaken the signals or clinical manifestations of liver diseases, which increases the difficulties in early diagnosis and treatment. ...

Role of cholestatic liver disease-related genes in intrahepatic cholestasis of pregnancy

Kan YanTing, Yang YongFeng

2019, 35(7): 1439-1443. DOI: 10.3969/j.issn.1001-5256.2019.07.006

Abstract(1588)

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Abstract:
Intrahepatic cholestasis of pregnancy ( ICP) is the most common liver disease during pregnancy. ICP usually occurs in late pregnancy, with main manifestations of pruritus, jaundice, and increases in serum levels of total bile acid and aminotransferases found by laboratory examination. ICP has great ...

Guidelines

Guidelines for the diagnosis and treatment of liver fibrosis in integrative medicine practice (2019)

Liver Disease Committee, Chinese Association of Integrative Medicine

2019, 35(7): 1444-1449. DOI: 10.3969/j.issn.1001-5256.2019.07.007

Abstract(1677)

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Abstract:

Clinical practice guidelines for laparoscopic hepatopancreatobiliary surgery

Development Committee of Clinical Practice Guidelines for Laparoscopic Hepatopancreatobiliary Surgery

2019, 35(7): 1450-1458. DOI: 10.3969/j.issn.1001-5256.2019.07.008

Abstract(1782)

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Abstract:

Clinical practice guidelines for robotic hepatopancreatobiliary surgery

Development Committee of Clinical Practice Guidelines for Robotic Hepatopancreatobiliary Surgery

2019, 35(7): 1459-1471. DOI: 10.3969/j.issn.1001-5256.2019.07.009

Abstract(1568)

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Abstract:

An excerpt of ASGE guideline on the role of endoscopy in the evaluation and management of choledocholithiasis (2019)

Lin Chuan, Li JiaSu, Liu Feng

2019, 35(7): 1472-1475. DOI: 10.3969/j.issn.1001-5256.2019.07.010

Abstract(501)

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Abstract:

Updated key points and clinical pathway for NCCN clinical practice guidelines in oncology: Pancreatic adenocarcinoma (Version2. 2019)

Meng ZhangTing, Li XiaoQing

2019, 35(7): 1476-1484. DOI: 10.3969/j.issn.1001-5256.2019.07.011

Abstract(326)

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Abstract:

Guideline Interpretation

Updated key points of Guidelines for the diagnosis and management of hepatic encephalopathy in cirrhosis ( 2018)

Li XiaoKe, Wang Shan, Li ZhiGuo, Gan DaNan, Ye YongAn

2019, 35(7): 1485-1488. DOI: 10.3969/j.issn.1001-5256.2019.07.012

Abstract(2078)

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Abstract:
In 2018, Chinese Society of Hepatology, Chinese Medical Association, issued Guidelines for the diagnosis and management of hepatic encephalopathy in cirrhosis, which gives recommendations for the clinical diagnosis and treatment of hepatic encephalopathy including minimal hepatic encephalopathy and ...

Original articles_Viral hepatitis

Current status of hepatitis B virus infection among pregnant women in Shaanxi Province, China and risk factors for mother-to-infant transmission

Yu Qiang, Wang Jing, Liu JinFeng, Yan TaoTao, Feng YaLi, He YingLi, Dai XiaoMin, Chen TianYan, Zhao YingRen, Zhu YaGe

2019, 35(7): 1489-1492. DOI: 10.3969/j.issn.1001-5256.2019.07.013

Abstract(1410)

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Abstract:
Objective To investigate the hepatitis B virus ( HBV) infection rate among pregnant women in Shaanxi Province, China and the high-risk population of mother-to-infant transmission ( MTIT) . Methods A survey was performed for 13 451 pregnant women in 18 hospitals in Shaanxi Province to investigate the...

Clinical effect of tenofovir disoproxil in treatment of chronic hepatitis B and its effect in blocking mother-to-child transmission of chronic hepatitis B during early pregnancy

Chen ChuanYing, Chen Fang, Cheng QuanHong, Tu XiangLin, Dai Ying, Lin Xue

2019, 35(7): 1493-1495. DOI: 10.3969/j.issn.1001-5256.2019.07.014

Abstract(1588)

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Abstract:
Objective To investigate the antiviral effect of tenofovir disoproxil ( TDF) in women with chronic hepatitis B ( CHB) and its effect in blocking mother-to-child transmission of CHB during early pregnancy. Methods A total of 164 pregnant women who were diagnosed with CHB in Nanchang Ninth Hospital fr...

Original articles_Liver fibrosis and liver cirrhosis

Effect of Xiaozhang plaster in treatment of cirrhotic ascites and its influence on the renin-angiotensin-aldosterone system

Li Shuang, Tao YanYan, Xing Feng, Zhao Qiang, Liu ChengHai

2019, 35(7): 1496-1500. DOI: 10.3969/j.issn.1001-5256.2019.07.015

Abstract(1423)

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Abstract:

Objective To investigate the effect of Xiaozhang plaster in the treatment of cirrhotic ascites and its influence on the renin-angiotensin-aldosterone system. Methods A total of 220 patients with cirrhotic ascites who were hospitalized in Department of Gastroenterology in Shanghai Baoshan Integrated ...

Predictive factors for third-generation cephalosporin-resistant spontaneous bacterial peritonitis

Zhu LongChuan, Gan DaKai, Hu QingQing, Xiong MoLong

2019, 35(7): 1501-1504. DOI: 10.3969/j.issn.1001-5256.2019.07.016

Abstract(1431)

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Abstract:

Objective To investigate the predictive factors for third-generation cephalosporin-resistant spontaneous bacterial peritonitis ( SBP) . Methods A retrospective analysis was performed for the clinical data of 206 patients with liver cirrhosis who were hospitalized in the Ninth Hospital of Nanchang fr...

Original articles_Liver neoplasms

Clinical significance of the management of adverse events and symptom cluster associated with advanced hepatocellular carcinoma after lenvatinib treatment

An LinJing, Zhang Xin, Yang Ying, Sha HuaYan, Huang Shun, Wang YaDong

2019, 35(7): 1505-1508. DOI: 10.3969/j.issn.1001-5256.2019.07.017

Abstract(2660)

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Abstract:
Objective To investigate the symptoms and symptom clusters in patients with advanced hepatocellular carcinoma ( HCC) receiving molecular-targeted therapy with lenvatinib, as well as the clinical significance of the management of symptoms and symptom clusters in reducing lenvatinib-related grade 3 or...

Clinical effect of transarterial chemoembolization with ultra-liquid iodized oil combined with drug-eluting beads in treatment of Barcelona Clinic Liver Cancer stage B/C hepatocellular carcinoma

Tang HaoHuan, Zhu XiaoLi, Wang WanSheng, Li WanCi, Zhou LinFeng, Du Hang

2019, 35(7): 1509-1513. DOI: 10.3969/j.issn.1001-5256.2019.07.018

Abstract(1595)

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Abstract:
Objective To investigate the clinical effect and safety of transarterial chemoembolization ( TACE) with ultra-liquid iodized oil combined with drug-eluting beads in the treatment of Barcelona Clinic Liver Cancer ( BCLC) stage B/C hepatocellular carcinoma ( HCC) .Methods A retrospective analysis was ...

Value of combined measurement of alpha-fetoprotein and alpha-fetoprotein L3% in the diagnosis of hepatocellular carcinoma

Guan GuiWen, Yao MingJie, Qian XiangJun, Zhai XiangWei, Yan XiaoTong, Zhao JingMin, Lu FengMin, Chen XiangMei

2019, 35(7): 1514-1519. DOI: 10.3969/j.issn.1001-5256.2019.07.019

Abstract(2306)

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Abstract:
Objective To investigate the value of combined measurement of alpha-fetoprotein ( AFP) and AFP-L3% in the diagnosis of hepatocellular carcinoma ( HCC) . Methods A retrospective analysis was performed for serological parameters and clinical data of 1208 patients with chronic hepatitis, 1967 patients ...

Establishment of Nomogram model of postoperative recurrence of primary hepatocellular carcinoma with reference to inflammatory cytokines

Gao SuHua, Gan HongYing, Wang Jun

2019, 35(7): 1520-1524. DOI: 10.3969/j.issn.1001-5256.2019.07.020

Abstract(1470)

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Abstract:
Objective To establish the Nomogram model of postoperative recurrence of hepatocellular carcinoma ( HCC) by collecting the data on clinical indices and inflammatory cytokines. Methods A total of 314 patients with HCC who were admitted to Wuhan Central Hospital from January 2014 to January 2016 and u...

Influence of monoacylglycerol lipase on growth of nude mice xenograft tumor of human hepatocellular carcinoma and related mechanism

Yu JiaJian, Zhang JunYong, Fan DeQing

2019, 35(7): 1525-1531. DOI: 10.3969/j.issn.1001-5256.2019.07.021

Abstract(1323)

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Abstract:
Objective To investigate the role and mechanism of action of monoacylglycerol lipase ( MAGL) on the growth of nude mice xenograft tumor of human hepatocellular carcinoma ( HCC) . Methods The transplanted SMMC-7721 cells were divided into SMMC-7721 WT group ( without treatment) , SMMC-7721 MAGL-KDgro...

Role of D-bifunctional protein in promoting the growth of hepatocellular carcinoma in rats and nude mice

Lu Xin, Liu Ying, Jia Lei, Kong LingYu, Liu DianQing

2019, 35(7): 1532-1535. DOI: 10.3969/j.issn.1001-5256.2019.07.022

Abstract(1436)

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Abstract:
Objective To investigate the expression of D-bifunctional protein ( DBP) in hepatocellular carcinoma ( HCC) tissue in rats and the growth of DBP-induced HCC in nude mice. Methods A total of 22 male Sprague-Dawley rats were randomly divided into normal control group with 8 rats and model group with 1...

Original articles_Pancreatic diseases

Association between dyslipidemia and acute pancreatitis: A prospective cohort study

Ji RuiGeng, Zhu GuoLing, Zhang Bing, Sun Qiu, Zhao Li, Li GuangJian, Cao LiYing

2019, 35(7): 1536-1540. DOI: 10.3969/j.issn.1001-5256.2019.07.023

Abstract(1462)

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Abstract:

Objective To investigate the influence of dyslipidemia and number of items conforming to the diagnostic criteria for dyslipidemia on new-onset acute pancreatitis ( AP) . Methods A prospective cohort study was performed for 99 695 on-the-job or retired workers of Kailuan Group who underwent the first...

Value of real-time elastography in predicting the risk of pancreatic fistula after pancreaticoduodenectomy

Wu YanBin, Zhu HuaMin, Wang XueWen, Niu HongKai, Cheng Yu

2019, 35(7): 1541-1545. DOI: 10.3969/j.issn.1001-5256.2019.07.024

Abstract(1376)

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Abstract:
Objective Objective To investigate the value of pancreatic elasticity based on shear wave elastography ( SWE) in predicting the risk of pancreatic fistula, to measure pancreatic hardness by determining the SWE level of the pancreatic body, and to reduce the development of pancreatic fistula after pa...

Original articles_Others

Clinical effect of glucocorticoids versus pentoxifylline in patients with severe alcoholic liver disease: A Meta-analysis

Yang Jun, Hu ZhongJie, Zhu YueKe, Yu HongWei, Li Juan, Hou Wei, Ning QiQi

2019, 35(7): 1546-1550. DOI: 10.3969/j.issn.1001-5256.2019.07.025

Abstract(532)

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Abstract:

Objective To systematically review the clinical effect of glucocorticoids used alone or in combination with pentoxifylline in patients with severe alcoholic liver disease. Methods PubMed, Embase, Chinese Scientific Journal Full-Text Database, CBM, China Scientific Journal Database, and Chinese Medic...

Interaction between Helicobacter pylori infection and polymorphisms of PPAR-γ2 gene Pro12Ala and GPx-1 gene Pro198Leu and its association with nonalcoholic fatty liver disease

Zhang ChaoXian, Guo LiKe, Zhang LiLi, Li GuangYan, Chang TingMin

2019, 35(7): 1551-1559. DOI: 10.3969/j.issn.1001-5256.2019.07.026

Abstract(2165)

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Abstract:

Objective To investigate the interaction between Helicobacter pylori infection and polymorphisms of PPAR-γ2 gene Pro12 Ala and GPx-1 gene Pro198 Leu and its association with nonalcoholic fatty liver disease ( NAFLD) . Methods A total of 750 patients with nonalcoholic fatty liver ( NAFL) , 750 patien...

Value of combined measurement of urinary insulin-like growth factor-binding protein 7 and tissue inhibitor of metalloproteinases-2 in predicting acute kidney injury associated with HBV-related acute-on-chronic liver failure

Li Ming, Chen RuLi, Wu ZhenPing, Cheng XiaoYu, Mei Qing, Zhang LunLi, Li XiaoPeng

2019, 35(7): 1560-1564. DOI: 10.3969/j.issn.1001-5256.2019.07.027

Abstract(1529)

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Abstract:

Objective To perform dynamic measurement of urinary insulin-like growth factor-binding protein 7 ( IFGBP7) and tissue inhibitor of metalloproteinases-2 ( TIMP-2) in patients with HBV-related acute-on-chronic liver failure ( HBV-ACLF) , and to investigate the value of combined measurement of urinary ...

Effect of recombinant human granulocyte colony-stimulating factor on rats with acute liver failure

Ha FuShuang, Han Tao, Liang Ning, Nie XinHua, Zhu ZhengYan

2019, 35(7): 1565-1569. DOI: 10.3969/j.issn.1001-5256.2019.07.028

Abstract(1295)

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Abstract:

Objective To investigate the effect of recombinant human granulocyte colony-stimulating factor ( rhG-CSF) on acute liver failure ( ALF) induced by D-galactosamine ( D-GalN) in rats. Methods A total of 105 male Sprague-Dawley rats were randomly divided into healthy control group, liver failure model ...

Protective effect of probiotics in rats with acute-on-chronic liver failure and related mechanism

Zhang YongChao, Bi YanZhen, Fang Xiao, Wang QuanYi, Wang QuanQuan, Tang HuiXin, Kong LingBin, Chen Yu, Duan ZhongPing, Shu ZhenFeng, Hong Feng

2019, 35(7): 1570-1575. DOI: 10.3969/j.issn.1001-5256.2019.07.029

Abstract(1518)

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Abstract:

Objective To investigate the effect of probiotics intervention on rats with acute-on-chronic liver failure ( ACLF) and related mechanism. Methods A total of 44 male Sprague-Dawley rats were randomly divided into six groups using a random number table, i. e., control group 1 ( C1 group with 6 rats wi...

Value of Gd-EOB-DTPA-enhanced MRI in the assessment of liver function in dogs with acute liver failure

Wang Hao, He Cheng, Chen Hao, Ou YangZhongMin, Liu ZhiQiang

2019, 35(7): 1576-1581. DOI: 10.3969/j.issn.1001-5256.2019.07.030

Abstract(1316)

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Abstract:

Objective To investigate the value of Gd-EOB-DTPA-enhanced MRI in the assessment of liver function in dogs with acute liver failure ( ALF) . Methods A total of 16 healthy adult male Beagle dogs were randomly divided into ALF group and blank control group, with 8 dogs in each group. The dogs in the A...

Brief reports

A study of construction strategy for regional clinical pathology center of liver disease based on SWOT analysis

Tang Hong, Xu RongRong, Jiang LiLin, Lu ZhongHua

2019, 35(7): 1582-1584. DOI: 10.3969/j.issn.1001-5256.2019.07.031

Abstract(1025)

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Abstract:

Case reports

Cirrhosis with capillary leak syndrome and hypothyroid myopathy: A case report

Zhou Yun, He WenGe, Huang ZhangXing

2019, 35(7): 1585-1587. DOI: 10.3969/j.issn.1001-5256.2019.07.032

Abstract(1117)

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Abstract:

Scleroderma with hepatic sarcoidosis: A case report

Zhang Yu, Shao YueMing, Yin Xin, Gao Hui, Xu Fang, Jin QingLong, Wen XiaoYu

2019, 35(7): 1588-1590. DOI: 10.3969/j.issn.1001-5256.2019.07.033

Abstract(1090)

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Abstract:

A case of hepatolenticular degeneration with neurological disorders as the prominent symptom

Lu: Jia, Zhao Gang, Sun XueHua, Gao YueQiu

2019, 35(7): 1591-1593. DOI: 10.3969/j.issn.1001-5256.2019.07.034

Abstract(1264)

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Abstract:

Low-molecular-weight heparin sodium for the treatment of hepatic sinusoidal obstruction syndrome: A case report

Jiang MinJie, Song LiSha, Xin GuiJie, Gao PuJun

2019, 35(7): 1594-1595. DOI: 10.3969/j.issn.1001-5256.2019.07.035

Abstract(1242)

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A case of lymphocytic interstitial pneumonia during corticosteroid treatment for autoimmune hepatitis

Xiong WeiJue, Cao Shan, Zhang GuoYan, Chen GuoDong, Wang ZhiFeng, Liu YuLan

2019, 35(7): 1596-1598. DOI: 10.3969/j.issn.1001-5256.2019.07.036

Abstract(1611)

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Abstract:

Primary biliary cholangitis with Sjogren's syndrome and immune thrombocytopenia: A case report

Chen QingLing, Kui YiWen, Zhong Rui, Yang QianQian, Zhang XiaoXue, Wen XiaoYu, Yu ChengNan, Jin QingLong

2019, 35(7): 1599-1600. DOI: 10.3969/j.issn.1001-5256.2019.07.037

Abstract(1435)

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Abstract:

Biliary stent implantation for malignant obstructive jaundice through the percutaneous transhepatic biliary drainage pathway: A report of 2 cases

Peng FengHui, Liu Kai, Yang Yang, Liu YaHui, Ji Bo

2019, 35(7): 1601-1603. DOI: 10.3969/j.issn.1001-5256.2019.07.038

Abstract(1372)

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Abstract:

Reviews

Mechanism of action of hypoxia-inducible factor 1α in the development and progression of liver fibrosis

Zhou Dan, Zhang LiTing, Li JunFeng, Wang Shan, Xiao Ping

2019, 35(7): 1604-1607. DOI: 10.3969/j.issn.1001-5256.2019.07.039

Abstract(1396)

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Abstract:

Liver fibrosis and end-stage liver cirrhosis are often accompanied by liver hypoxia. As a key transcription factor for regulating the body's response to hypoxia, hypoxia-inducible factor 1α ( HIF-1α) plays an important role in the activation of hepatic stellate cells and the development and progress...

Clinical value of albumin-bilirubin grade in evaluating the prognosis of hepatocellular carcinoma

Luo Hao, Huang Jun

2019, 35(7): 1608-1612. DOI: 10.3969/j.issn.1001-5256.2019.07.040

Abstract(2353)

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Abstract:
Hepatocellular carcinoma ( HCC) is one of the most common primary malignant tumors in the world, and although there are various therapeutic methods for HCC, its prognosis remains unsatisfactory. Albumin-bilirubin ( ALBI) grade is a new clinical index which can be used to evaluate liver function and ...

Role of intestinal microflora in the pathogenesis of hepatocellular carcinoma

Zheng Wei, Zhang YongHong, Zhao Yan

2019, 35(7): 1613-1615. DOI: 10.3969/j.issn.1001-5256.2019.07.041

Abstract(1278)

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Abstract:
Hepatocellular carcinoma ( HCC) is the most common type of primary liver cancer and is one of the complications of chronic liver diseases. Recent experimental and clinical studies have shown that the gut-liver axis plays a key role in the pathogenesis of chronic liver diseases including HCC. Change ...

Expression of vascular endothelial growth factor receptors and invasion and metastasis of hepatocellular carcinoma

Li CunDi, Cao WeiYa, Wang Jian

2019, 35(7): 1616-1620. DOI: 10.3969/j.issn.1001-5256.2019.07.042

Abstract(1096)

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Abstract:
Vascular endothelial growth factor receptors ( VEGFRs) consist of three receptor tyrosine kinase ( RTK) superfamily members and two non-RTK superfamily members and bind to the ligand in a non-one-to-one way. VEGFRs mediate various signaling pathways such as Raf1→MAP2 K1/2→ERK1/2 through cell surface...

Research advances in the pathogenesis of nonalcoholic fatty liver disease-related hepatocellular carcinoma

Liu SuTong, Zhao WenXia

2019, 35(7): 1621-1625. DOI: 10.3969/j.issn.1001-5256.2019.07.043

Abstract(1061)

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Abstract:
The incidence rate of nonalcoholic fatty liver disease-related hepatocellular carcinoma ( NAFLD-HCC) is gradually increasing.Its pathogenesis is associated with the changes in genetic and epigenetic modifications, metabolism, immunity, intestinal microecology, endocrine pathways, and circadian rhyth...

Association between chemokines and nonalcoholic fatty liver disease

Chu PeiLing, Wang Qi, Guo XiaoQing, Liu JinChun

2019, 35(7): 1626-1628. DOI: 10.3969/j.issn.1001-5256.2019.07.044

Abstract(1279)

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Abstract:
In recent years, the incidence rate of nonalcoholic fatty liver disease ( NAFLD) keeps increasing, and the age of onset tends to become younger. NAFLD has become one of the major public health problems in the 21 st century. This article reviews the research advances in the association between some c...

Mechanism of action of microRNA in the regulation of hepatic ischemia-reperfusion injury

Zhang ShiLong, Peng CiJun, Feng ZanJie, Gao WeiDong, Duan YuLing, Fan GuoXin

2019, 35(7): 1629-1631. DOI: 10.3969/j.issn.1001-5256.2019.07.045

Abstract(1275)

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Abstract:
Hepatic ischemia-reperfusion injury is one of the most important factors affecting the prognosis of clinical hepatic surgery. Studies have shown that microRNAs can participate in the process of hepatic ischemia-reperfusion injury through multiple pathways. This article reviews the biosynthesis and f...

Research advances in mutation characteristics of the UGT1A1 gene in Gilbert syndrome and its influence on intrahepatic and extrahepatic systems

Liang Chen, Bai Li, Zheng SuJun

2019, 35(7): 1632-1635. DOI: 10.3969/j.issn.1001-5256.2019.07.046

Abstract(1923)

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Abstract:
Gilbert syndrome is the most common type of hereditary hyperbilirubinemia with a high incidence rate. This article briefly describes the research advances in epidemiological characteristics of Gilbert syndrome, common UGT1 A1 gene mutation sites, and the influence of Gilbert syndrome on intrahepatic...

Role of microRNA in the pathogenesis, diagnosis, and outcome evaluation of primary biliary cholangitis

Wang Jing, Zhang BiQing, Pan YunZhi, Zhu ChuanWu

2019, 35(7): 1636-1639. DOI: 10.3969/j.issn.1001-5256.2019.07.047

Abstract(434)

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Abstract:

Primary biliary cholangitis ( PBC) is one of common autoimmune liver diseases, and its pathogenesis remains unclear. This article summarizes the role of microRNA in the pathogenesis, diagnosis, and outcome evaluation of PBC and points out that microRNA may be involved in the development and progress...

Value of percutaneous transhepatic choledochoscopic lithotripsy in treatment of hepatolithiasis

Liu XinWen, Cheng Yao, Gong JianPing

2019, 35(7): 1640-1643. DOI: 10.3969/j.issn.1001-5256.2019.07.048

Abstract(1323)

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Abstract:
Hepatolithiasis is a common benign biliary disease in China. It is a challenge to treat hepatolithiasis. Some patients with complicated hepatolithiasis fail to achieve satisfactory outcomes after several biliary operations, and therefore, how to improve the treatment outcome of hepatolithiasis is a ...

Research advances in perioperative management of hilar cholangiocarcinoma

Jiang Hua, Wang YueHua

2019, 35(7): 1644-1647. DOI: 10.3969/j.issn.1001-5256.2019.07.049

Abstract(1371)

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Abstract:
Hilar cholangiocarcinoma ( HCCA) is a common malignant tumor of the biliary system with great difficulties in surgery, and there are still controversies over the standardized diagnosis and treatment system of HCCA. This article reviews the research advances in perioperative management of HCCA, inclu...