2018 No. 7

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Editorial

Immunotherapy for hepatocellular carcinoma

Ren ZhengGang

2018, 34(7): 1371-1373. DOI: 10.3969/j.issn.1001-5256.2018.07.001

Abstract(2428)

PDF (1593KB)(415) Cited By (11)

Abstract:
In the past 10 years, the progress in systemic therapy for hepatocellular carcinoma ( HCC) is attributed to the application of molecular target therapy and the improvement in immunotherapy. The immunosuppressive microenvironment of HCC enables HCC cells to avoid attack by the immune system, which is...

Discussions by experts

Progress in the prevention and treatment of HBV-related hepatocellular carcinoma

Dong Jing, Jiang JiaJi

2018, 34(7): 1374-1377. DOI: 10.3969/j.issn.1001-5256.2018.07.002

Abstract(2848)

PDF (1548KB)(480) Cited By (5)

Abstract:
Hepatitis B virus ( HBV) -related hepatocellular carcinoma ( HCC) accounts for 63. 9% of all HCC cases in mainland China.HBV leads to the development or recurrence of HCC in a direct or indirect way. Theoretically, anti-HBV therapy can reduce or delay the development of HCC. There has been convincin...

Value of Gd-EOB-DPTA in the diagnosis of hepatocellular carcinoma

Li RuoKun, Yan FuHua, Li Ke

2018, 34(7): 1378-1381. DOI: 10.3969/j.issn.1001-5256.2018.07.003

Abstract(2262)

PDF (1539KB)(384) Cited By (4)

Abstract:
Gd-EOB-DPTA is a hepatocyte-specific contrast agent with the function of double-contrast imaging. It can reflect the blood supply of lesions via dynamic enhancement imaging and show the change in the expression of molecular receptors on hepatocyte membrane via hepatobiliary phase imaging. Gd-EOB-DPT...

Clinical predictive models for individualized treatment of hepatocellular carcinoma

Wang Kui, Zou QiFei, Shen Feng, Li Zheng, Wei WenXin, Xia Yong, Li Jun, Yan ZhenLin

2018, 34(7): 1382-1386. DOI: 10.3969/j.issn.1001-5256.2018.07.004

Abstract(2790)

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Abstract:
Hepatocellular carcinoma ( HCC) is one of the most common malignant tumors in China and has high incidence and mortality rates. HCC is often accompanied by hepatitis and liver cirrhosis, and therefore, there is high demand for precise treatment based on disease stage, tumor location, and liver funct...

Advances in molecular targeted therapy for hepatocellular carcinoma

Chen WanYong, Ren Ning

2018, 34(7): 1387-1394. DOI: 10.3969/j.issn.1001-5256.2018.07.005

Abstract(2456)

PDF (1579KB)(511) Cited By (14)

Abstract:
At present, the main treatment methods for hepatocellular carcinoma ( HCC) include surgery, chemotherapy, and radiotherapy.With the development of molecular biological techniques, the field of molecular targeted therapy is developing rapidly. The design of targeted drugs based on some specific sites...

Value of common laboratory parameters in predicting the prognosis of hepatocellular carcinoma

Wen XiaJie, Yao MingJie, Zhang Ling, Lu FengMin

2018, 34(7): 1395-1398. DOI: 10.3969/j.issn.1001-5256.2018.07.006

Abstract(2703)

PDF (1540KB)(444) Cited By (12)

Abstract:
Patients with hepatocellular carcinoma ( HCC) often have underlying liver diseases, and unlike other types of cancer, the features of HCC and residual liver function may affect patient survival after surgery. In order to help clinicians identify patients who can benefit from radical hepatectomy, thi...

Prevalence of primary liver cancer in Eastern countries and related influencing factors

Zhang MingYuan, Niu JunQi

2018, 34(7): 1399-1402. DOI: 10.3969/j.issn.1001-5256.2018.07.007

Abstract(2573)

PDF (1708KB)(604) Cited By (109)

Abstract:
Primary liver cancer is a serious disease which threatens human health, and Eastern countries have a high prevalence rate of primary liver cancer. Data from the World Health Organization show that in recent years, the incidence rate of liver cancer tends to decrease in most Eastern countries, and he...

Therapeutic guidelines

Technical guidelines for clinical evaluation of liver injury induced by traditional Chinese medicine

State Drug Administration

2018, 34(7): 1403-1409. DOI: 10.3969/j.issn.1001-5256.2018.07.008

Abstract(2120)

PDF (1668KB)(501) Cited By (34)

Abstract:

An excerpt of EASL clinical practice guidelines on hepatitis E virus infection 2018

Li Yan, Tang ShanHong

2018, 34(7): 1410-1414. DOI: 10.3969/j.issn.1001-5256.2018.07.009

Abstract(2011)

PDF (1535KB)(379) Cited By (2)

Abstract:

An excerpt of EASL clinical practice guidelines: Management of alcohol-related liver disease (2018)

Song Yang, Zhou Fei, Chen LiGang

2018, 34(7): 1415-1419. DOI: 10.3969/j.issn.1001-5256.2018.07.010

Abstract(357)

PDF (209KB)(328) Cited By (6)

Abstract:

Comparison and interpretation of Chinese, American, and European guidelines on alcoholic liver diseases

Yang Song, Xing HuiChun, Cheng Jun

2018, 34(7): 1420-1422. DOI: 10.3969/j.issn.1001-5256.2018.07.011

Abstract(1984)

PDF (1524KB)(398) Cited By (13)

Abstract:

Original articles_Viral hepatitis

Clinical features of HBV-related liver failure associated with recurrence after withdrawal of nucleos ( t) ide analogues and influencing factors for prognosis

Li XiaoLou, Zhuo HaiYan, Liu ZhiQiang, Chen RuanQin, Chen Li

2018, 34(7): 1423-1427. DOI: 10.3969/j.issn.1001-5256.2018.07.012

Abstract(2350)

PDF (1562KB)(406) Cited By (16)

Abstract:
Objective To investigate the clinical features of chronic hepatitis B ( CHB) patients progressing to liver failure due to recurrence after withdrawal of nucleos ( t) ide analogues and influencing factors for prognosis. Methods A retrospective analysis was performed for the clinical data of 40 patien...

Association of N-glycosylation mutation of HBV envelope protein with the development and prognosis of acute-on-chronic liver failure in patients with chronic hepatitis B

Chen Jie, Yao MingQi, Wei FeiLi, Xu JinFeng, Guo LeLe, Yang HaiXia, Li Ming, Zhang Jing

2018, 34(7): 1428-1431. DOI: 10.3969/j.issn.1001-5256.2018.07.013

Abstract(2429)

PDF (1551KB)(384) Cited By (1)

Abstract:
Objective To investigate the association of N-glycosylation mutation of HBV envelope protein with the development of acute-on-chronic liver failure ( ACLF) in patients with chronic hepatitis B ( CHB) . Methods A total of 90 patients with HBV-ACLF were enrolled, and 60 patients with CHB were enrolled...

Original articles_Liver fibrosis and liver cirrhosis

Influence of daclatasvir hydrochloride combined with asunaprevir on renal function in patients with compensated hepatitis C cirrhosis

Liang ZhiJun, Wang SuNa

2018, 34(7): 1432-1435. DOI: 10.3969/j.issn.1001-5256.2018.07.014

Abstract(2196)

PDF (1660KB)(393) Cited By (4)

Abstract:
Objective To investigate the influence of daclatasvir hydrochloride combined with asunaprevir on renal function in patients with compensated hepatitis C cirrhosis. Methods A total of 44 previously untreated patients with compensated hepatitis C cirrhosis caused by hepatitis C virus genotype 1 b infe...

Correlation between serum selenium level and degree of liver cirrhosis in Enshi, Hubei Province, China

Zheng XiaoLi, He JianHua, Xiang XingChao, Zhou XiangYu, Lei Lei

2018, 34(7): 1436-1439. DOI: 10.3969/j.issn.1001-5256.2018.07.015

Abstract(1961)

PDF (1538KB)(372) Cited By (2)

Abstract:
Objective To investigate the serum selenium level in patients with cirrhosis in Enshi, Hubei Province, China. Methods A total of 90 patients with cirrhosis who were treated in The Central Hospital of Enshi Autonomous Prefecture from January 2016 to June 2017 were enrolled as liver cirrhosis group an...

Anesthetic effect and adverse reactions of propofol in painless gastrointestinal endoscopy in patients with different Child-Pugh classification of liver cirrhosis

Gao Fang, Chang Yue, Li Hai

2018, 34(7): 1440-1444. DOI: 10.3969/j.issn.1001-5256.2018.07.016

Abstract(2144)

PDF (1554KB)(335) Cited By (13)

Abstract:
Objective To investigate the anesthetic effect and adverse reactions of propofol in painless gastrointestinal endoscopy in patients with varying degrees of liver cirrhosis. Methods A total of 342 patients with liver cirrhosis who underwent gastrointestinal endoscopy under propofol anesthesia in The ...

Risk factors for early rebleeding after first-time endoscopic variceal ligation

Cui CanCan, Li DanDan, Li ZhangFeng, Yan ZhenKun, Wang LiQiang, Sun Chen, Zhang Ke, Zhang Bin

2018, 34(7): 1445-1451. DOI: 10.3969/j.issn.1001-5256.2018.07.017

Abstract(2524)

PDF (1822KB)(395) Cited By (17)

Abstract:
Objective To investigate the effect of endoscopic variceal ligation ( EVL) for the first time on liver function in patients with liver cirrhosis and the risk factors for early rebleeding after surgery. Methods A retrospective analysis was performed for the clinical data of 125 cirrhotic patients wit...

Original articles_Liver neoplasms

Clinical effect of selective transcatheter arterial embolization combined with CT-guided microwave ablation in treatment of hepatic hemangioma

Lu NingNing, Wang HaiYan, Gao WenFeng, Zhang YongHong, Zheng JiaSheng

2018, 34(7): 1452-1455. DOI: 10.3969/j.issn.1001-5256.2018.07.018

Abstract(1847)

PDF (1688KB)(316) Cited By (14)

Abstract:
Objective To investigate the clinical effect and safety of selective transcatheter arterial embolization ( TAE) combined with CT-guided microwave ablation in the treatment of hepatic hemangioma, and to provide a reference for the selection of treatment methods for hepatic hemangioma. Methods A retro...

Clinical features of patients with Barcelona Clinic Liver Cancer stage C primary liver cancer and related prognostic factors: An analysis of 140 cases

Guo XiaoDi, Sun ShaSha, Li WenDong, Shen YanJun, Sun Wei, Ding XiaoYan, Chen JingLong

2018, 34(7): 1456-1461. DOI: 10.3969/j.issn.1001-5256.2018.07.019

Abstract(2609)

PDF (2941KB)(337) Cited By (22)

Abstract:
Objective To investigate the clinical features of patients with Barcelona Clinic Liver Cancer ( BCLC) stage C primary liver cancer ( PLC) and related prognostic factors. Methods A retrospective analysis was performed for the clinical data of 140 patients with BCLC stage C PLC who were admitted to Be...

Clinical effect of sequential therapy with transarterial chemoembolization and bipolar-needle radiofrequency ablation in treatment of hepatocellular carcinoma in high-risk locations

Liang HongYuan, Guo QiYong, Mao XiaoNan, Sun Wei, Zhao Gang, Wang XiHai, Liu Zhen, Wen Feng, Lu ZaiMing

2018, 34(7): 1462-1469. DOI: 10.3969/j.issn.1001-5256.2018.07.020

Abstract(2215)

PDF (1843KB)(362) Cited By (4)

Abstract:
Objective To investigate the clinical effect of sequential therapy with transarterial chemoembolization ( TACE) and bipolar-needle radiofrequency ablation ( RFA) in the treatment of hepatocellular carcinoma ( HCC) in high-risk locations. Methods A total of 35 previously untreated patients with HCC i...

Clinical value of serum PIVKA-Ⅱ in diagnosis of HBV-related hepatocellular carcinoma

Zhang Ying, Yan XueBing

2018, 34(7): 1470-1474. DOI: 10.3969/j.issn.1001-5256.2018.07.021

Abstract(2554)

PDF (1630KB)(399) Cited By (3)

Abstract:
Objective To evaluate the clinical value of serum protein induced by vitamin K absence or antagonist-Ⅱ ( PIVKA-Ⅱ) and alpha-fetoprotein ( AFP) , alone or in combination, in the diagnosis of hepatitis B virus ( HBV) -related hepatocellular carcinoma ( HCC) . Methods A total of 450 patients with HBV i...

Association between the expression of centromere protein F and prognosis in patients with hepatocellular carcinoma:An analysis using GEO database

Fan Bin, Zhang Yong, Li JinMao, Liu Tao, Zhang JiaYao

2018, 34(7): 1475-1480. DOI: 10.3969/j.issn.1001-5256.2018.07.022

Abstract(3166)

PDF (1811KB)(469) Cited By (5)

Abstract:
Objective To investigate the association of the expression of centromere protein F ( CENPF) with clinical features and prognosis in patients with hepatocellular carcinoma ( HCC) . Methods The online tool Oncomine was used to measure the expression of CENPF in HCC tissue and normal liver tissue. Rela...

ECHS1, epidermal growth factor, and low-glucose conditions promote the invasion and metastasis of hepatocellular carcinoma cells

Lu JiaZhen, Xu WenJuan, Cai YiLing, Ao ShaoJun, Ding RongRong, Zhang MingQing

2018, 34(7): 1481-1486. DOI: 10.3969/j.issn.1001-5256.2018.07.023

Abstract(2726)

PDF (2272KB)(390) Cited By (5)

Abstract:
Objective To investigate the expression of key enzymes associated with energy metabolism in hepatocellular carcinoma ( HCC) tissue, as well as the roles of short-chain enoyl-CoA hydratase 1 ( ECHS1) , AMP-activated protein kinase ( AMPK) , fatty acid synthase ( FAS) , acetyl-CoA carboxylase ( ACC) ,...

Construction of the eukaryotic expression vectors of interleukin-12 and granulocyte-macrophage colony-stimulating factor and their expression in hepatoma cells

Shao Xue, Ma JingTing, Song Jie, Zhang Qian, Zhang ChuanHui, Wang WuDong, Wu Meng, Pan LiuLan

2018, 34(7): 1487-1491. DOI: 10.3969/j.issn.1001-5256.2018.07.024

Abstract(2173)

PDF (2428KB)(360) Cited By (1)

Abstract:
Objective To construct the eukaryotic expression vectors of interleukin-12 ( IL-12) and granulocyte-macrophage colony-stimulating factor ( GM-CSF) , PBI-CMV3-IL-12 and PBI-CMV3-GM-CSF, and the expression of IL-12 and GM-CSF in hepatoma cells after H22 hepatoma cells are transfected with such vectors...

Specific magnetic resonance imaging of vascular endothelial growth factor-C targeted molecular probe and its clinical significance in a rat model of hepatocellular carcinoma

Pan Qi, Luo ChunHai, Ma WanLing, Qu YuanFei, Wang JianRu, Chen Lin

2018, 34(7): 1492-1496. DOI: 10.3969/j.issn.1001-5256.2018.07.025

Abstract(2190)

PDF (1796KB)(346) Cited By (6)

Abstract:
Objective To investigate the magnetic resonance ( MR) imaging features of the targeted molecular probe with vascular endothelial growth factor-C ( VEGF-C) antibody and superparamagnetic iron oxide ( USPIO) , VEGF-C-USPIO, in a rat model of hepatocellular carcinoma ( HCC) and its clinical significanc...

Original articles_Biliary diseases

Value of direct peroral cholangioscopy combined with laser lithotripsy in treatment of patients with difficult common bile duct stones

Chen XiaoQin, Liu XiongChang, Yang JunJie, Zhang QiYong, Liu TianRang

2018, 34(7): 1497-1501. DOI: 10.3969/j.issn.1001-5256.2018.07.026

Abstract(2080)

PDF (1894KB)(395) Cited By (9)

Abstract:
Objective To investigate the clinical effect of direct peroral cholangioscopy combined with laser lithotripsy in the treatment of difficult bile duct stones. Methods A total of 21 patients with difficult bile duct stones who underwent cholecystolithotomy under endoscopic retrograde cholangiopancreat...

Clinical effect of primary suture versus T-tube drainage in laparoscopic choledocholithotomy: A meta-analysis

Zhou Ze, Wang GuoTai, Yang XingWu

2018, 34(7): 1502-1507. DOI: 10.3969/j.issn.1001-5256.2018.07.027

Abstract(2692)

PDF (1796KB)(458) Cited By (62)

Abstract:
Objective To investigate the clinical effect, adaptability, and advantages/disadvantages of primary suture versus T-tube drainage in laparoscopic common bile duct exploration ( LCBDE) , and to provide reliable evidence for clinical treatment. Methods Pub Med, OVID, WOS, EMBASE, Chinese Scientific Jo...

Original articles_Others

Value of MELD score, MELD-Na score, and King's College Hospital criteria in evaluating the prognosis of patients with acute liver failure of pregnancy

Han PuQing, Sun Yan

2018, 34(7): 1508-1513. DOI: 10.3969/j.issn.1001-5256.2018.07.028

Abstract(2094)

PDF (1659KB)(361) Cited By (10)

Abstract:

Objective To investigate the value of the Model for End-Stage Liver Disease ( MELD) score, MELD combined with serum sodium concentration ( MELD-Na) score, and King's College Hospital ( KCH) criteria in evaluating the prognosis of patients with acute liver failure ( ALF) of pregnancy. Methods A total...

Case reports

Clonorchiasis complicated by multiple cholelithiasis and cholestatic cirrhosis misdiagnosed as Budd-Chiari syndrome: A case report

Xu YanLing, Zhao Xu, Guo XiaoLin, Ji HuiFan, Zhang Ying, Song XinYue, Wang JingYu, Sun XiaoFeng, Liu Kai, He RongHua, Gao PuJun

2018, 34(7): 1514-1516. DOI: 10.3969/j.issn.1001-5256.2018.07.029

Abstract(2050)

PDF (1622KB)(428) Cited By (8)

Abstract:

Diagnosis and treatment of idiopathic portal hypertension: A case report

Li LiangTao, Wu Bo, Wang ShouQian, Wang YingChao

2018, 34(7): 1517-1519. DOI: 10.3969/j.issn.1001-5256.2018.07.030

Abstract(2074)

PDF (1659KB)(386)

Abstract:

A case of large hepatocellular carcinoma treated by transcatheter arterial chemoembolization combined with radiofrequency ablation

Liu BoZhi, Yuan ZhuHui, Li Wei

2018, 34(7): 1520-1522. DOI: 10.3969/j.issn.1001-5256.2018.07.031

Abstract(1810)

PDF (1750KB)(341) Cited By (3)

Abstract:

Successful treatment and clinical cure of acute-on-chronic liver failure in third trimester of pregnancy: A case report

Wang YaPing, Shi YuMing, Xu Min, Yang Zhan, Li Jing, Chen Keng, Liu HuiYuan

2018, 34(7): 1523-1525. DOI: 10.3969/j.issn.1001-5256.2018.07.032

Abstract(2047)

PDF (1527KB)(360) Cited By (3)

Abstract:

Clinical effect of double plasma molecular absorption system in treatment of liver failure due to hyperthyroidism: A case report

Guo XiJu, Guo WeiBo, Zhang JiaChang, Lu YaJing, Yang Yan

2018, 34(7): 1526-1528. DOI: 10.3969/j.issn.1001-5256.2018.07.033

Abstract(2054)

PDF (1527KB)(412) Cited By (3)

Abstract:

Autoimmune hepatitis with thrombotic thrombocytopenic purpura: A case report

Wu Yun, Yao ZhiShan, Wang Wei

2018, 34(7): 1529-1531. DOI: 10.3969/j.issn.1001-5256.2018.07.034

Abstract(2334)

PDF (1655KB)(387) Cited By (1)

Abstract:

A case of hepatic sinusoidal obstruction syndrome

Hu ZhiFeng, Yin ShiWu, Pan ShengQuan, Xiang TingMiao

2018, 34(7): 1532-1534. DOI: 10.3969/j.issn.1001-5256.2018.07.035

Abstract(1910)

PDF (1878KB)(418) Cited By (1)

Abstract:

A case of double gallbladder malformation with obstructive jaundice

Li HongHong, Zhao Ge, Xue JunJun, Ning YaWen, Guo HongYi, Li WenLong, Guo ChunLei

2018, 34(7): 1535-1537. DOI: 10.3969/j.issn.1001-5256.2018.07.036

Abstract(1640)

PDF (1940KB)(319) Cited By (2)

Abstract:

Reviews

Research advances in extrahepatic manifestations of chronic hepatitis C virus infection

Liu JingWen, Hao YingXia, Gao GuangZhou

2018, 34(7): 1538-1542. DOI: 10.3969/j.issn.1001-5256.2018.07.037

Abstract(1483)

PDF (1561KB)(331) Cited By (1)

Abstract:
As a hepato-and lymphotropic virus, hepatitis C virus ( HCV) not only infects hepatocytes, but also replicates in extrahepatic tissues and peripheral blood mononucleated cells. Chronic HCV infection is known to be associated with a wide variety of extrahepatic manifestations, such as hematological d...

Analysis of reversal factors associated with liver fibrosis/cirrhosis in patients with chronic HBV infection after achieving virologic response

Yang Yan, Zhang Xin

2018, 34(7): 1543-1546. DOI: 10.3969/j.issn.1001-5256.2018.07.038

Abstract(1589)

PDF (1557KB)(323) Cited By (10)

Abstract:
Chronic hepatitis B virus ( HBV) infection can lead to varying degrees of liver fibrosis, which is an important pathological basis of liver cirrhosis. The incidence of end-stage liver diseases such as liver cirrhosis and hepatocellular carcinoma can be reduced by controlling and even reversing liver...

Research advances in the role of coagulation factors in liver fibrosis

Li SuXin, Li LuHao, Dang XiaoWei

2018, 34(7): 1547-1550. DOI: 10.3969/j.issn.1001-5256.2018.07.039

Abstract(1384)

PDF (1538KB)(354) Cited By (4)

Abstract:
Present studies on organ fibrosis including liver fibrosis show that coagulation factors and inflammatory response promote the progression of organ fibrosis, which makes people to be aware of the fact that the change in coagulation factors is not only a secondary event to liver fibrosis, and coagula...

Clinical effect of rifaximin in treatment of complications associated with liver cirrhosis

Lu: XinYue, Li Lei

2018, 34(7): 1551-1554. DOI: 10.3969/j.issn.1001-5256.2018.07.040

Abstract(1723)

PDF (1539KB)(335) Cited By (14)

Abstract:
Patients with liver cirrhosis often die of complications, among which hepatic encephalopathy is the primary cause of death and upper gastrointestinal bleeding is the most common complication of liver cirrhosis. In recent years, with the continuous progress in the research on intestinal flora and inf...

Current status of research on primary and secondary risk factors for esophagogastric variceal rebleeding in patients with liver cirrhosis

He Yang, Su YaRong, Han ZiYan

2018, 34(7): 1555-1559. DOI: 10.3969/j.issn.1001-5256.2018.07.041

Abstract(1534)

PDF (1564KB)(316) Cited By (10)

Abstract:
There are various risk factors for esophagogastric variceal bleeding ( EVB) in patients with liver cirrhosis, such as portal hypertension, thrombosis and blood coagulation in the ruptured blood vessel, sclerotic region or number of ligation points, internal environment, degree of risk of malnutritio...

Role of immunosuppressive cells in the development and progression of hepatocellular carcinoma

Zang ChaoRan, Zhang YongHong

2018, 34(7): 1560-1564. DOI: 10.3969/j.issn.1001-5256.2018.07.042

Abstract(1690)

PDF (1563KB)(351) Cited By (3)

Abstract:
Hepatocellular carcinoma ( HCC) is a major health problem around the world. The incidence rate of HCC is gradually increasing, but its early diagnostic rate remains at a low level. Most patients who present with apparent clinical symptoms have reached the advanced stage, which greatly influences the...

Research advances in glucocorticoids for the treatment of liver failure

Wang XiuFang, Feng GuoHe

2018, 34(7): 1565-1568. DOI: 10.3969/j.issn.1001-5256.2018.07.043

Abstract(2032)

PDF (1548KB)(441) Cited By (17)

Abstract:
Glucocorticoids ( GCs) are widely used in the treatment of liver diseases accompanied by inflammation due to its strong anti-inflammatory and immunosuppressive effects, especially autoimmune hepatitis and cholestatic hepatitis. However, there are still controversies over the use of GCs in the treatm...

Research advances in autoimmune hepatitis and primary biliary cholangitis in 2017

Li ShuXiang, Duan WeiJia, Zhang Dong, You Hong, Jia JiDong

2018, 34(7): 1569-1572. DOI: 10.3969/j.issn.1001-5256.2018.07.044

Abstract(2122)

PDF (1548KB)(479) Cited By (6)

Abstract:
Autoimmune liver diseases are a group of chronic liver injuries mediated by abnormal autoimmunity and mainly include autoimmune hepatitis ( AIH) , primary biliary cholangitis ( PBC) , and primary sclerosing cholangitis. With the continuous improvement in people's understanding of these diseases and ...

Association of regulatory T cells, T helper 17 cells, and change in their balance with autoimmune hepatitis

Ge KuanXue, Gao WeiHua, Xiang XiaoXing

2018, 34(7): 1573-1576. DOI: 10.3969/j.issn.1001-5256.2018.07.045

Abstract(2155)

PDF (1552KB)(320) Cited By (4)

Abstract:
Autoimmune hepatitis ( AIH) is a chronic liver inflammatory disease, and its etiology and pathogenesis remain unclear. In recent years, abnormal immune regulation mechanism has become a research hotspot. Regulatory T ( Treg) cells and Th17 cells are two subsets of CD4+T cells and there are significa...

Progress in diagnosis and treatment of pyogenic liver abscess

Zhang ShunYi, Chen YueXiang

2018, 34(7): 1577-1580. DOI: 10.3969/j.issn.1001-5256.2018.07.046

Abstract(2803)

PDF (1541KB)(728) Cited By (50)

Abstract:
Pyogenic liver abscess ( PLA) is a common hepatic infectious disease. Early, sufficient intravenous injection of sensitive antibiotics combined with percutaneous drainage has led to a decrease in the mortality of PLA in recent years. And clinicians can diagnose and locate the disease quickly with th...

Research advances in the diagnosis and treatment of serous microcystic adenoma of pancreas

Han Jie, Zhang YongSheng, Kong XinLiang, Sun WenBing

2018, 34(7): 1581-1584. DOI: 10.3969/j.issn.1001-5256.2018.07.047

Abstract(2077)

PDF (1754KB)(329) Cited By (3)

Abstract:
Serous microcystic adenoma of pancreas ( SMAP) is a rare type of serous cystadenoma of the pancreas, and its major pathological features include the formation of many small sacs around the central stellate scar and glycogen-rich cubic epithelial cells with the same shape in the sacs. SMAP has a low ...