As a radical treatment for hepatocellular carcinoma( HCC),liver transplantation( LT) brings new hope for the treatment of HCC,but tumor recurrence and metastasis after LT remain the most important factor that affects the outcome of LT in HCC. The comprehensive strategy,including investigating the bi...

With the continuous development for half a century,auxiliary liver transplantation and related techniques have become more mature,and the major indications are also expanding. This article reviews the history of auxiliary liver transplantation and introduces its indications,including metabolic liver...

With the establishment of reasonable selection criteria and continuous technical refinement,living donor liver transplantation( LDLT) has been widely performed in the world. Right- lobe LDLT has become the conventional procedure performed at many centers. In recent years,due to the considerations of...

Liver transplantation has become the effective therapeutic method for end- stage liver disease,but the incidence of biliary complications after liver transplantation remains high. With an increasing number of liver transplantation procedures from donation after cardiac death( DCD),it is necessary to...

Immune induction therapy with antibodies has been widely applied in liver transplantation. This paper introduces common antibodies for immune induction and their application in liver transplantation,and points out that immune induction therapy with antibodies reduces the dosage of hormones and calci...

With the development of organ transplantation techniques and the improvement of immunotherapies,liver transplantation( LT)has been developing rapidly and has become the most effective method for treating end- stage liver diseases. However,acute and chronic rejection reactions and ischemia- reperfusi...

Objective To observe the clinical effect and safety of direct- acting antiviral agents( DAAs) in patients with hepatitis C recurrence after liver transplantation. Methods Fifteen patients who received liver transplantation in 302 Hospital of PLA from December 2014 to May 2015 were selected,and after...

Objective To investigate the association of Model for End- Stage Liver Disease( MELD) score with complications and early survival rate after liver transplantation for benign end- stage liver disease,and to analyze the criteria to select donor livers with fatty liver for patients with different MELD ...

Objective To observe the occurrence of hypophosphatemia induced by adefovir dipivoxil( ADV) for the treatment of chronic hepatitis B and investigate the association between intact fibroblast growth factor 23( i FGF23) and occurrence of hypophosphatemia,and to find a new way for early discovery and p...

Objective To investigate the association between Helicobacter pylori( Hp) infection and stages of liver pathology in patients with chronic hepatitis B( CHB). Methods Seventy- nine patients who were hospitalized in the People's Hospital of Liuzhou from February 2008 to December 2014 were selected,and...

Objective To explore the clinical significance of serum hepatitis B virus large surface protein( LHB),HBs Ag,hepatitis B virus( HBV) DNA,and alanine aminotransferase( ALT) levels and their correlation with liver inflammation activity in patients with chronic hepatitis B( CHB). Methods One hundred an...

Objective To investigate the application of pericardial devascularization and omental packing combined with gastric noose cerclage in the treatment of portal hypertension. Methods The clinical data of 59 patients who were treated in our hospital and received pericardial devascularization and omental...

Objective To investigate the risk factors associated with early postoperative recurrence of hepatocellular carcinoma( HCC) after surgical resection,and to discuss the predictive value of preoperative ultrasound examination for early recurrence of HCC after surgical resection. Methods The clinical da...

Objective To investigate the association between CD4~+/ CD8~+ratio in peripheral blood and patient prognosis after hepatectomy for liver cancer. Methods The clinical data of 150 patients who received partial hepatectomy for liver cancer in the 180 Hospital of PLA from October 2008 to November 2011 w...

Objective To investigate the application value of transpancreatic septotomy with pancreatic duct stent or guide wire in difficult endoscopic retrograde cholangiopancreatography( ERCP). Methods A total of 309 patients who underwent difficult ERCP in Medical Center for Digestive Diseases,The Second Af...

Objective To investigate the expression of Toll- like receptor 4( TLR4) in the rat model of nonalcoholic fatty liver disease( NAFLD). Methods A total of 16 specific pathogen- free Sprague- Dawley rats were divided into normal group and NAFLD group,with8 rats in each group,and in the NAFLD group,a ra...

Objective To investigate the effect of polyinosinic- polycytidylic acid( poly I∶ C) on the activation of natural killer cells( NK cells)in the mouse model of liver injury induced by carbon tetrachloride( CCl4). Methods Eighty C57BL/6 mice were randomly divided into normal control group,poly I∶ C con...

For patients with chronic hepatitis C who undergo liver transplantation,recurrence of hepatitis C virus( HCV) infection after liver transplantation has always been a great challenge in the medical field. With our increased understanding of HCV replication cycle,the appearance of direct- acting antiv...

Primary biliary cirrhosis( PBC) is an autoimmune liver disease which progresses slowly,and its pathogenesis remains unclear. A total of 29 papers reporting the risk factors for PBC from different perspectives were obtained through Google Scholar search and screening,consisting of 19 reviews and 10 r...

Cavernous transformation of the portal vein( CTPV) is considered a rare condition. However,with the development of radiological technology,an increasing number of patients have been diagnosed with CTPV,thus causing wide attention in clinical practice. This article elaborates on the research advances...

Hepatic myelopathy is a rare neurological complication which is caused by various acute or chronic liver diseases. It is clinically characterized by progressive spastic paraplegia of both lower extremities. The pathogenesis of this disease is unclear,and there is a lack of effective treatments as we...

Thymosin β4 exists in most human tissues and cells,involved in many physiological and pathological processes in the human body,such as anti- inflammation,wound healing,angiogenesis,and tumor metastasis. In recent years,thymosin β4 has been found to play an important role in the development and progr...

Monoclonal antibodies( m Abs) have a high specificity and have been widely used in various diseases,especially in the treatment and study of liver injury induced by viruses. In recent years,human m Abs directly prepared from single B lymphocytes have been getting more and more attention due to high ...

Pancreatic fistula,a common complication after pancreaticoduodenectomy,is a severe condition with a high mortality. Therefore,early diagnosis of this condition and effective prevention and treatment measures are essential. This article reviews the diagnostic criteria for pancreatic fistula,the risk ...