中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R

2013 No. 2

Display Method:
Discussions by experts
Recent progress in research of hepatitis B viruses with precore and basic core promoter mutations
Li JinE, Chen XinYue
2013, 29(2): 88-92. DOI:
Abstract:

Mutations in the precore and basic core promoter of hepatitis B virus (HBV) can reduce synthesis and secretion of the HBV e antigen (HBeAg) , increase viral replication, and cause HBeAg-negative chronic hepatitis B (CHB) .Therefore, these mutations are likely to have important impacts on the clinica...