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血清及胆汁CEA、CA19-9、CA24-2在胆道良恶性梗阻性疾病中的诊断价值

刘涛 罗耀兵 张家耀

刘涛, 罗耀兵, 张家耀. 血清及胆汁CEA、CA19-9、CA24-2在胆道良恶性梗阻性疾病中的诊断价值[J]. 临床肝胆病杂志, 2018, 34(2): 327-331. DOI: 10.3969/j.issn.1001-5256.2018.02.021.
引用本文: 刘涛, 罗耀兵, 张家耀. 血清及胆汁CEA、CA19-9、CA24-2在胆道良恶性梗阻性疾病中的诊断价值[J]. 临床肝胆病杂志, 2018, 34(2): 327-331. DOI: 10.3969/j.issn.1001-5256.2018.02.021.
Liu Tao, Luo YaoBing, Zhang JiaYao. Value of serum and biliary carcinoembryonic antigen, carbohydrate antigen 19-9, and carbohydrate antigen 24-2 in diagnosis of benign and malignant biliary obstructive diseases[J]. J Clin Hepatol, 2018, 34(2): 327-331. DOI: 10.3969/j.issn.1001-5256.2018.02.021.
Citation: Liu Tao, Luo YaoBing, Zhang JiaYao. Value of serum and biliary carcinoembryonic antigen, carbohydrate antigen 19-9, and carbohydrate antigen 24-2 in diagnosis of benign and malignant biliary obstructive diseases[J]. J Clin Hepatol, 2018, 34(2): 327-331. DOI: 10.3969/j.issn.1001-5256.2018.02.021.

血清及胆汁CEA、CA19-9、CA24-2在胆道良恶性梗阻性疾病中的诊断价值

DOI: 10.3969/j.issn.1001-5256.2018.02.021
详细信息
  • 中图分类号: R575

Value of serum and biliary carcinoembryonic antigen, carbohydrate antigen 19-9, and carbohydrate antigen 24-2 in diagnosis of benign and malignant biliary obstructive diseases

  • 摘要:

    目的探讨血清及胆汁CEA、CA19-9、CA24-2检测对胆道良恶性梗阻性疾病的诊断价值。方法选择2015年6月-2016年12月来恩施土家族苗族自治州中心医院诊治的良性和恶性胆道梗阻患者各40例,收集入院时的血清和手术中的胆汁标本进行肿瘤标志物(CEA、CA19-9及CA24-2)检测。2组间比较采用t检验,并对各肿瘤标志物诊断胆道良恶性梗阻性疾病进行受试者工作特征曲线分析。结果胆道恶性梗阻性疾病组血清CA19-9、CA24-2水平均明显高于胆道良性梗阻性疾病组,差异均有统计学意义(t值分别为5.899、3.223,P值均<0.05)。胆道恶性梗阻性疾病组胆汁CEA、CA19-9及CA24-2水平均明显高于胆道良性梗阻性疾病组,差异均有统计学意义(t值分别为3.304、7.615、7.279,P值均<0.05)。胆道恶性梗阻性疾病组胆汁中肿瘤标志物CEA、CA19-9及CA24-2水平均明显高于血清,差异均有统计学意义(t值分别为3.297、4.975、3.993,P值均<0.05);其中胆汁CA24-2的约登指数和受试者工作特征曲线下面积(AUC)最高,分别为0....

     

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  • 收稿日期:  2017-08-14
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