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FibroScan与FibroTouch对肝纤维化程度诊断价值的比较分析

吴娜 张明媛 吴瑞红 张璎文 金晶兰 祝英乔 牛俊奇

引用本文:
Citation:

FibroScan与FibroTouch对肝纤维化程度诊断价值的比较分析

DOI: 10.3969/j.issn.1001-5256.2014.07.012
基金项目: 

国家自然青年科学基金(81301415);国家自然青年科学基金(81101237); 

详细信息
  • 中图分类号: R575.2

Diagnostic values of FibroScan and FibroTouch for liver fibrosis: a comparative analysis

Research funding: 

 

  • 摘要: 目的比较FibroScan与FibroTouch对肝纤维化程度的诊断价值。方法收集2013年9月-2014年3月就诊于吉林大学第一医院肝胆胰内科的患者962例,同时行FibroScan和FibroTouch检测。其中33例有肝穿刺病理分期,66例可计算天冬氨酸转氨酶与血小板比值指数(APRI)(53例慢性乙型肝炎,13例慢性丙型肝炎)。2种检测值之间的相关性采用Spearman秩相关检验。利用受试者工作特征曲线(ROC)分析2种检测方法对肝纤维化程度的诊断价值,并进行比较。结果对所有患者FibroScan与FibroTouch的测量值进行分析,FibroScan与FibroTouch的相关系数为0.866(P<0.05,n=962),与APRI的相关系数分别为0.58、0.63(P<0.05,n=66),与肝穿刺病理分期的相关系数分别为0.67、0.74(P<0.05,n=33)。对于慢性乙型肝炎患者,FibroScan与FibroTouch诊断APRI分期≥2的ROC曲线下面积(AUC)分别为0.761和0.728,两者差异无统计学意义(P=0.61);对于慢性丙型...

     

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  • 收稿日期:  2014-06-24
  • 出版日期:  2014-07-20
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