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肝硬化与睡眠障碍

吴鉴今 姚定康

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肝硬化与睡眠障碍

详细信息
  • 中图分类号: R575.2

Recent advances in understanding the relations between liver cirrhosis and sleep disorders

  • 摘要:

    肝硬化患者常表现出睡眠障碍,最新研究显示睡眠障碍或许与肝硬化患者不良预后有关。本文讨论睡眠障碍与肝性脑病(HE)和肝肺综合征(HPS)等肝硬化并发症之间的关系,并对其在原发性胆汗性肝硬化、丙型肝炎、非酒精性脂肪肝、wilson病等几种特殊病因引起的肝硬化中的作用作一综述。

     

  • [1]Jiang H, Xie Q.Advances in the diagnosis and treatment of hepaticencephalopathy[J].J Clin Hepatol, 2011, 27 (10) :1027-1031. (in Chinese) 姜浩, 谢青.肝性脑病临床诊治的进展[J].临床肝胆病杂志, 2011, 27 (10) :1027-1031.
    [2] Mostacci B, Ferlisi M, Baldi Antognini A, et al.Sleep disturbance anddaytime sleepiness in patients with cirrhosis:a case control study[J].Neurol Sci, 2008, 29 (4) :237-240.
    [3]Montagnese S, Middleton B, Skene DJ, et al.Night-time sleepdisturbance does not correlate with neuropsychiatric impairment inpatients with cirrhosis[J].Liver Int, 2009, 29 (9) :1372-1382.
    [4]Jiménez-Anguiano A, Díaz-Medina V, Farfán-Labonne BE, etal.Modification of sleep architecture in an animal model of experi-mental cirrhosis[J].World J Gastroenterol, 2009, 15 (41) :5176-5180.
    [5]Kanwal F, Gralnek IM, Hays RD, et al.Health-related quality oflife predicts mortality in patients with advanced chronic liver disease[J].Clin Gastroenterol Hepatol, 2009, 7 (7) :793-799.
    [6]Lu DY, Wen B, He F.Clincal efficacy of naloxone in treatment ofhepatic encephalopathy[J].J Clin Exp Med, 2012, 11 (9) :703, 705. (in Chinese) 陆德云, 温彪, 何峰.纳洛酮治疗肝性脑病的临床疗效观察[J].临床和实验医学杂志, 2012, 11 (9) :703, 705.
    [7]Wei X, Cheng WL, Zhang RZ.A Clinical study of rhubarb decoc-tion in treatment of mild hepatic encephalopathy[J].J Chang chunUni Tradit Chin Med, 2011, 27 (1) :26-27.韦新, 程万里, 张荣臻.大黄煎剂治疗轻微肝性脑病的临床研究[J].长春中医药大学报, 2011, 27 (1) :26-27.
    [8]Marchetti P, D'Avanzo C, Orsato R.Electroencephalography in pa-tients with cirrhosis[J].Gastroenterology, 2011, 141 (5) :1680-1689.e1-2.
    [9]Llansola M, Cantero JL, Hita-Yanez E, et al.Progressive reduc-tion of sleep time and quality in rats with hepaticencephalopathycaused by portacaval shunts[J].Neuroscience, 2012, 201:199-208.
    [10]Farjam M, Dehdab P, Abbassnia F, et al.Thioacetamide-inducedacute hepatic encephalopathy in rat:behavioral, biochemical andhistological changes[J].Iran Red Crescent Med J, 2012, 14 (3) :164-170.
    [11]Mostacci B, Ferlisi M, Baldi AA, et al.Sleep disturbance and daytimesleepiness in patients with cirrhosis:a casecontrol study[J].NeurolSci, 2008, 29 (4) :237-240.
    [12]Montagnese S, Middleton B, Skene DJ, et al.Night-time sleepdisturbance does not correlate with neuropsychiatric impairment inpatients with cirrhosis[J].Liver Int, 2009, 29 (9) :1372-1382.
    [13]Spahr L, Coeytaux A, Giostra E, et al.Histamine H1 blockerhydroxyzine improves sleep in patients with cirrhosis andminimalhepatic encephalopathy:a randomized controlled pilot trial[J].Am J Gastroenterol, 2007, 102 (4) :744-753.
    [14]Palma DT, Philips GM, Arguedas MR, et al.Oxygen desaturationduring sleep in hepatopulmonary syndrome[J].Hepatology, 2008, 47 (4) :1257-1263.
    [15]Halank M, Langner S, Kolditz M, et al.Nocturnal oxygen desaturationis a frequent complication in portopulmonary hypertension[J].Z Gas-troenterol, 2008, 46 (11) :1260-1265.
    [16]Jones DE, Al-Rifai A, Frith J, et al.The independent effects of fa-tigue and UDCA therapy on mortality in primary biliary cirrhosis:re-sults of a 9 year follow-up[J].J Hepatol, 2010, 53 (5) :911-917.
    [17]Jones DE, Newton JL.An open study of modafinil for the treatmentof daytime somnolence and fatigue in primary biliary cirrhosis[J].Aliment Pharmacol Ther, 2007, 25 (4) :471-476.
    [18]Hardy T, MacDonald C, Jones DE, et al.A follow-up study ofmodafinil for the treatment of daytime somnolence and fatigue in pri-mary biliary cirrhosis[J].Liver Int, 2010, 30 (10) :1551-1552.
    [19]Carlson MD, Hilsabeck RC, Barakat F, et al.Role of sleep dis-turbance in chronic hepatitis C infection[J].Curr Hepat Rep, 2010, 9 (1) :25-29.
    [20]Raison CL, Rye DB, Woolwine BJ, et al.Chronic interferon-al-pha administration disrupts sleep continuity and depth in patientswith hepatitis C:association with fatigue, motor slowing, and in-creased evening cortisol[J].Biol Psychiatry, 2010, 68 (10) :942-949.
    [21]Sockalingam S, Abbey SE, Alosaimi F, et al.A review of sleepdisturbance in hepatitis C[J].J Clin Gastroenterol, 2010, 44 (1) :38-45.
    [22]de Almeida CM, de Lima TA, Castro DB, et al.Immunological/virological peripheral blood biomarkers and distinct patterns of sleep-ing quality in chronic hepatitis C patients[J].Scand J Immunol, 2011, 73 (5) :486-495.
    [23]Rabkin JG, McElhiney MC, Rabkin R.Modafinil and armodafinil treat-ment for fatigue for HIV-positive patients with and without chronic hepa-titis C[J].Int J STD AIDS, 2011, 22 (2) :95-101.
    [24]Martin KA, Krahn LE, Balan V, et al.Modafinil's use in comba-ting interferon-induced fatigue[J].Dig Dis Sci, 2007, 52 (4) :893-896.
    [25]Chin K, Nakamura T, Takahashi K, et al.Effects of obstructive sleepapnea syndrome on serum aminotransferase levels in obese patients[J].Am J Med, 2003, 114 (5) :370-376.
    [26]Shpirer I, Copel L, Broide E, et al.Continuous positive airwaypressure improves sleep apnea associated fatty liver[J].Lung, 2010, 188 (4) :301-307.
    [27]Kohler M, Pepperell JC, Davies RJ, et al.Continuous positive air-way pressure and liver enzymes in obstructive sleep apnoea:datafrom a randomized controlled trial[J].Respiration, 2009, 78 (2) :141-146.
    [28]Piguet AC, Stroka D, Zimmermann A, et al.Hypoxia aggravates non-alcoholic steatohepatitis in mice lacking hepatocellular PTEN[J].ClinSci (Lond) , 2010, 118 (6) :401-410.
    [29]Spisni E, Valerii MC, Manerba M, et al.Effect of copper on extra-cellular levels of key pro-inflammatory molecules in hypothalamicGN11 and primary neurons[J].Neurotoxicology, 2009, 30 (4) :605-612.
    [30]Nevsimalova S, Buskova J, Bruha R, et al.Sleep disorders in Wilson's disease[J].Eur J Neurol, 2011, 18 (1) :184-190.
    [31]Netto AB, Sinha S, Taly AB, et al.Sleep in Wilson's disease:questionnaire based study[J].Ann Indian Acad Neurol, 2011, 14 (1) :31-34.
    [32]Netto AB, Sinha S, Taly AB, et al.Sleep in Wilson's disease:apolysomnography-based study[J].Neurol India, 2010, 58 (6) :933-938.
    [33]Franco RA, Ashwathnarayan R, Deshpandee A, et al.The highprevalence of restless legs syndrome symptoms in liver disease in anacademic-based hepatology practice[J].J Clin Sleep Med, 2008, 4 (1) :45-49.
    [34]Rodrigue JR, Nelson DR, Reed AI, et al.Fatigue and sleep qualitybefore and after liver transplantation[J].Prog Transplant, 2010, 20 (3) :221-233.
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  • 出版日期:  2013-05-20
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