Pediatric liver diseases associated with infection
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摘要: 儿童时期各种嗜肝病毒和其他病毒感染以及各种细菌、真菌等不同病原体感染都可累及肝脏,肝脏病变常为全身感染的一部分,较少引起典型的肝炎症状,也可出现严重的肝损伤。机体免疫状态与临床特征密切相关。急性病毒性肝炎病理多为肝脏全小叶细胞的弥漫性变性,慢性肝炎特征为肝实质与汇管区的炎症与纤维化等。不同细菌、真菌感染可引起肝脏化脓性病变,也可以肉芽肿的病变为主,需要综合全面分析临床资料等确诊。Abstract: All types of pathogenic hepatotropic viruses and other viruses, bacteria and fungi may cause liver diseases in children.As one of the component of multisystem disease, the symptoms of viral hepatitis may be atypical in most pediatric-aged patients.But severe liver injury may occur in few cases.The immune status is significantly associated with clinical manifestations.The characteristics of pathology of acute viral hepatitis is the presence of diffuse degeneration and necrosis of single or groups of parenchymal cells.The characteristics of chronic hepatitis is the presence inflammatory infiltrate and fibrosis in liver parenchyma and portal area.Some bacteria, fungi and other pathogens infection may cause pyogenic liver abscess and granulomas.Intensive investigations may be required for definite diagnosis.
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Key words:
- liver diseases /
- hepatitis
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