肝硬化腹水治疗的研究现状与展望

邱玲; 胡玉琳

肝硬化腹水治疗的研究现状与展望

邱玲,
胡玉琳

吉林大学第一医院肝胆胰内科

详细信息

中图分类号: R575.2
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- 被引次数: 0
出版历程
- 出版日期: 2010-06-20

Recent status and prospect of ascites treatment in cirrhosis patients

Qiu Ling,
Hu YuLin

摘要

摘要: 腹水是肝硬化最常见的并发症,并与发生感染、稀释性低钠血症、肾功能衰竭和病死率增加密切相关。无并发症的少量腹水患者早期处理原则是,休息加上低钠饮食。中等量腹水患者,一般选择低剂量利尿剂就能达到利尿效果。大量腹水患者,可大量放腹水+静点白蛋白（8g/每放腹水1000ml）。顽固性腹水患者,可用重复多次大量放腹水+血浆扩容治疗或用经颈静脉肝内门体分流术（TIPS）治疗。新药（如V2受拮抗剂和血管收缩剂等）对肝硬化腹水的治疗可能带来希望。
- 肝硬化 /
- 腹水
Abstract: Ascites is the most common complication in cirrhosis, and is closely related to the increased mortality due to infection, diluted hyponatremia and renal failure.Rest and sodium restriction are the components of the managements of uncomplicated mild ascites.Low dose diuretics are effective in patients with moderate ascites.Furthermore, the large-volume paracentesis (LVP) with albumin administration (8 g/L of ascites removed) are the treatment of choice for the management of patients with large ascites.As to the refractory ascites, methods for treatment include repeated LVP with plasma expander or transjugular intrahepatic portosystemic shunt (TIPS) .New medicines such as vasoconstrictors and V2-receptors of vasopressin maybe beneficial in patients with ascites in liver cirrhosis.
- liver cirrhosis /
- ascites

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参考文献(19)

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