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胰腺炎导致门静脉系统血栓形成发病机制及其防治方法的探讨

孙文静 陈东风

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胰腺炎导致门静脉系统血栓形成发病机制及其防治方法的探讨

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  • 中图分类号: R576

Probe into the pathogenesis and control methods of thrombopoiesis in portal system associated with pancreatitis

  • 摘要: <正>胰腺炎是多种病因导致胰酶在胰腺内被激活后引起胰腺组织自身消化、水肿、出血、坏死的炎症反应,或导致胰腺局部、节段性、弥漫性慢性进展性炎症。在急性胰腺炎(acute pancreatitis,AP)早期,胰腺细胞损伤导致局部的炎症反应,随着炎症细胞因子对胰腺组织的第二次打击,可出现全身炎症反应

     

  • [1]Weber SM, Deshmukh HL, Mathur SK.Extensive portal and splen-ic vein thrombosis:differences in hemodynamics and management[J].Hepato-Gastroenterology, 2003, 50 (52) ∶1085-1089.
    [2]Izbicki JR, Yekebas EF, Strate T, et al.Extrahepatic portal hyper-tension in chronic pancreatitis:old problem revisited[J].AnnSurg, 2002, 236 (1) ∶82-89.
    [3]姚戈冰, 鲁建国.门静脉血栓的发病机制及诊治[J].肝胆外科杂志, 2009, 4 (17) ∶151-154.
    [4]Zhang XP, Li ZJ, Zhang J.Inflammatory mediators and microcircu-latory disturbance in acute pancreatitis[J].Hepatobiliary PacreatDis Int, 2009, 8 (4) ∶351-357.
    [5]Novovic S, Andersen AM, Erboll AK, et al.Proinflammatory cyto-kines in alcohol or gallstone induced acute pancreatitis[J].A pro-spective study.JOP, 2009, 10 (3) ∶256-262.
    [6]Mohamed EW.A case of portal vein thrombosis associated with a-cute cholecystitis/pancreatitis or coincidence[J].HepatobiliaryPancreat Dis Int, 2006, 5 (2) ∶308-310.
    [7]Zhang XP, Ye Q, Jiang XG, et al.Preparation method of an idealmodel of multiple organ injury of rat with severe acutepancreatitis[J].World J Gastroenterol, 2007, 13 (34) ∶4566-4573.
    [8]周卫华.静脉血栓栓塞症与炎性细胞因子[J].临床医药实践杂志, 2004, 13 (7) ∶484.
    [9]Liras G, Carballo F.An impaired phagocytic function is associatedwith leucocyte activation in the early stages of severe acute pancrea-titis[J].Gut, 1996, 39 (1) ∶39-42.
    [10]Hackert T, Pfeil D, Hartwig W, et al.Platelet function in acute ex-perimental pancreatitis induced by ischaemia-reperfusion[J].Br JSurg, 2005, 92 (6) ∶724-728.
    [11]DoboszM, Hac S, Mionskowska L, et al.Organ microcirculatorydisturbances in experimental acute pancreatitis, a role of nitric oxide[J].Physio Res, 2005, 54 (4) ∶363-368.
    [12]Lundberg AH, Granger DN, Russell J, et al.Quantitative measure-ment of P-and E-selectin adhesion molecules in acute pancreati-tis:correlation with distant organ injury[J].Ann Surg, 2000, 231 (2) ∶213-222.
    [13]王振文.急性胰腺炎凝血功能变化及机制研究[D].天津医科大学, 2007.
    [14]雷新, 韩本立.Tuftsin及其抑制物的化学合成和对巨噬细胞抗胆管癌作用的影响[J].免疫学杂志, 2000, 16 (2) ∶110-113.
    [15]余莉, 成雨, 罗建飞.吞噬雌激素及其抑制物对急性胰腺炎胰腺微血栓影响的实验研究[J].微循环杂志, 2004, 14 (4) ∶52-54.
    [16]Noel RA, Braun DK, Patterson RE, et al.Increased risk of acutepancreatitis and billiary disease observed in patients with type 2 dia-betes:a retrospective cohort study[J].Diabetes Care, 2009, 32 (5) ∶834-883.
    [17]王刚, 孙备, 姜洪池.高脂血症急性胰腺炎的研究进展[J].中国普通外科杂志, 2005, 14 (11) ∶777-779.
    [18]陈振祥, 白桦, 白桂香, 等.急性胰腺炎患者凝血、抗凝血功能的变化及意义[J].中国实验诊断学, 2003, 7 (4) ∶92-93.
    [19]Morioka C, Uemura M, Matsuyama T, et al.Plasma ADAMTS13activity parallels the APACHE II score, reflecting an early prognos-tic indicator for patients with severe acute pancreatitis[J].Scand JGastroenterol, 2008, 43 (11) ∶1387-1396.
    [20]中华医学会外科学分会胰腺外科学组.重症急性胰腺炎诊治指南[J].中华外科杂志, 2007, 45 (11) ∶727-728.
    [21]陶京, 王春友.重症胰腺炎早期临床救治的几个重要方面[J].肝胆外科杂志, 2005, 2 (13) ∶11-13.
    [22]方力争, 金燕, 朱涛.液体负平衡在重症急性胰腺炎治疗中的意义[J].中国急救医学, 2004, 24 (3) ∶231.
    [23]蔡敏, 吴建新, 李力, 等.液体复苏对重症胰腺炎胰组织微血栓形成的影响[J].中国病理生理杂志, 2008, 24 (12) ∶2418-2422.
    [24]Machado MCC, Coelho AMM, Pontieri V, et al.Local and system-ic effects of hypertonic solution (NaCl 7.5%) in experimental a-cute pancreatitis[J].Pancreas, 2006, 32 (1) ∶80-85.
    [25]Coelho AMM, Jukemura J, Lindkvist B, et al.Hypertonic salinesolution inhibits systemic inflammatory response but not local lesionin experimental acute pancreatitis[J].Pancreas, 2007, 35 (4) ∶396-397.
    [26]Qiu FL, Huang XS, Lv XS, et al.Effect of low molecular weightheparin on pancreatic microcirculation in severe acute pancreatitis ina rodent model[J].Chinese Medical Journal, 2007, 120 (24) ∶2260-2263.
    [27]Leizorovicz A.Comparison of the efficacy and safety of low molecu-lar weight heparins and unfractionated heparin in the initial treat-ment of deep venous thrombosis, an updated meta-analysis[J].Drug, 1996, 52 (Suppl 7) ∶30-37.
    [28]孙中杰, 王自法, 潘承恩.右旋糖苷在急性胰腺炎治疗中的作用[J].肝胆外科杂志, 1999, 5 (7) ∶403-404.
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