PDF下载 ( 118 KB)
Clinical significance of determining serum prealbumin in patients with viral hepatitis.
-
摘要: 了解病毒性肝炎患者血清前白蛋白 (PA)的变化 ,探讨测定血清前白蛋白对病毒性肝炎患者的诊断价值。采用免疫比浊法检测 2 76例病毒性肝炎患者血清前白蛋白 ,比较不同临床类型的血清PA的水平及同一临床类型间PA与A的异常率。血清PA的水平在急性肝炎与轻度慢性肝炎之间、慢性肝炎轻度与中度、中度与重度之间、肝硬化与慢性重型肝炎之间均有显著性差异 (P <0 0 5 ) ;急性肝炎组PA与白蛋白 (A)两者相比有高度显著性差异 (P <0 0 0 1) ;PA值比A值更灵敏地反映肝功能损害。血清PA的水平持续 <10 0mg/L作为重症肝炎早期诊断指标之一。检测血清PA对病毒性肝炎临床诊断、病情判断和预后估计有一定参考价值Abstract: To investigate the significance of prealbumin in liver diseases and to discuss the diagnostic value of determining serum prealbumin in viral hepatitis.The serum leve of prealbumin was detected in 276 cases liver diseases by immunoturbidimetry.The serum prealbumin lever in patients with acute hepatitis and mild chronic hepatitis mild chronic and maderate chronic moderate and severe cirrhosis and chronic severe hepatitis were significantly different respectively (P<0.05) ;there was significant difference in serum prealbunin level between prealbumin and albunin in acute hepatitis group (P<0.001) .Serum prealbumin levels could reflect the degrees of liver damages to some extent.Determining serum prealbumin is helpful of diagnosing viral hepatitis, judging state of the illness and estimating the prognosis.
-
Key words:
- prealbumin /
- viral hepatitis
-
[1]王宝恩, 张定凤.现代肝脏病学[M ].北京:科学出版社, 2003∶194～196. [2]漆德芳, 孟申, 刘健.肝硬化[M ].北京:科学技术出版社, 2000∶227～228. [3]林益振.多指标评估肝脏储备功能[J].国外医学临床生物化学与检验学分册, 1996, 17 (3) ∶113～115. [4] 张建荣, 徐德安, 周岳松, 等.血清前白蛋白在肝病检测中临床意义的探讨[J].中华医药荟萃杂志, 2002, 6 (3) ∶20～21. [5]张卫卫, 王学清, 李岩.血清前白蛋白、胆碱酯酶对判断肝硬化患者肝储备功能及预后的临床价值[J].中国实用内科杂志, 2002, 11 (22) ∶673～674. [6]章芳, 曾晓波, 苏先狮, 等.血清前白蛋白在各类乙型肝炎检测中的意义[J].临床肝胆病杂志, 2001, 8 (17) ∶163～164. [7]陈东海, 严泽彪.血清胆碱酯酶及前白蛋白测定在判断肝脏合成功能中的应用[J].现代诊断与治疗, 2002, 13 (6) ∶333～335. [8]范顺富, 吴俊琪.血清前白蛋白对肝病的诊断价值[J].浙江预防医学, 2000, 12 (6) ∶14～15 -
本文二维码
计量
- 文章访问数: 2522
- HTML全文浏览量: 24
- PDF下载量: 1077
- 被引次数: 0
下载:
