肝硬化血氨相关肝性脑病的诊治思考
DOI: 10.3969/j.issn.1001-5256.2023.12.028
利益冲突声明:本文不存在任何利益冲突。
作者贡献声明:张亮参与拟定写作思路及撰写文章;李浩参与指导撰写文章及论文修改;汤善宏负责拟定写作思路,指导撰写文章及最后定稿。
Thoughts on the diagnosis and treatment of hepatic encephalopathy associated with blood ammonia in liver cirrhosis
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摘要: 肝性脑病是肝硬化的严重并发症,可引起神经精神症状,如认知功能障碍和运动障碍等。超过30%的肝硬化患者会发生肝性脑病,给患者造成了巨大的经济负担,也给临床诊治带来了很多挑战。因此,早期发现和诊治是改善患者预后的关键。本文结合本中心的临床经验,从发病机制、时间维度、轻微型肝性脑病及脑部非器质性病变方面进行阐述,以期对肝硬化肝性脑病的临床诊治提供新的思路或策略。Abstract: Hepatic encephalopathy is a serious complication of liver cirrhosis and can cause neuropsychiatric symptoms such as cognitive impairment and motor impairment. More than 30% of patients with liver cirrhosis may develop hepatic encephalopathy, posing a huge economic burden to the health of patients and bringing many challenges to clinical diagnosis and treatment. Therefore, early identification, diagnosis, and treatment are the key to improving patient prognosis. Based on the clinical experience of our center, this article elaborates on hepatic encephalopathy from the aspects of pathogenesis, time dimension, minimal hepatic encephalopathy, and non-organic brain lesions, in order to provide new ideas or strategies for the diagnosis and treatment of hepatic encephalopathy in liver cirrhosis.
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Key words:
- Liver Cirrhosis /
- Hepatic Encephalopathy /
- Diagnosis
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