中医药治疗肝病疗效评价体系构建与思考

牛倩倩; 陈薇; 李秀惠

doi:10.12449/JCH260501

中医药治疗肝病疗效评价体系构建与思考

DOI: 10.12449/JCH260501

牛倩倩¹,
陈薇²,
李秀惠^3, , ,

1.
首都医科大学附属北京中医医院肝病科，北京 100010
2.
北京中医药大学循证医学中心，北京 100029
3.
首都医科大学附属北京佑安医院中西医结合中心，北京 100069

利益冲突声明：本文不存在任何利益冲突。

作者贡献声明：牛倩倩负责论文撰写、整理及修订；陈薇负责审阅和方法学审核；李秀惠负责研究思路设计和学术指导。

详细信息

通信作者:
李秀惠， lixiuhui@sohu.com （ORCID： 0000-0002-6707-2693）

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- 被引次数: 0
出版历程
- 收稿日期: 2026-03-24
- 录用日期: 2026-04-21
- 出版日期: 2026-05-20

Construction and consideration on a traditional Chinese medicine efficacy evaluation system for liver diseases

Qianqian NIU¹,
Wei CHEN²,
Xiuhui LI^{3
, ,
,}

1.
Department of Hepatology，Beijing Hospital of Traditional Chinese Medicine，Capital Medical University，Beijing 100010，China
2.
Center for Evidence-Based Chinese Medicine，Beijing University of Chinese Medicine，Beijing 100029，China
3.
Center for Integrated Traditional Chinese and Western Medicine，Beijing YouAn Hospital，Capital Medical University，Beijing 100069，China

More Information

Corresponding author: LI Xiuhui， lixiuhui@sohu.com （ORCID： 0000-0002-6707-2693）

摘要

摘要: 中医药治疗肝病具有独特优势，但传统疗效评价主观性强、标准化不足，现代医学评价标准又难以契合中医药干预特色，“病-症-证分离”现象突出。针对上述问题，本文提出以“病-症-证结合”为核心理念，构建融合中医证候疗效、患者报告结局、疾病总体转归、生物学指标演变的四维疗效评价体系。文章系统阐释了各维度核心内涵、指标遴选原则及量化方法，明确体系实施原则与具体实施策略，旨在为推动中医肝病领域开展高质量临床研究、产出高级别循证证据提供方法学支撑，助力中医药诊疗的现代化及国际化传播。
- 肝疾病 /
- 中医药疗法 /
- 治疗结果
Abstract: Traditional Chinese medicine （TCM） has unique advantages in the management of liver diseases； however， traditional TCM efficacy evaluation is highly subjective with a lack of standardized criteria， and the evaluation criteria for modern medicine are incompatible with the characteristics of TCM interventions， leading to a marked dissociation between diseases， symptoms， and syndromes. To address the above issues， this article proposes the core principle of disease-symptom-syndrome integration and establishes a four-dimensional efficacy evaluation system including TCM syndrome efficacy， patient-reported outcomes， overall disease prognosis， and changes in biological indicators. This article systematically elaborates on the core connotation， indicator selection criteria， and quantification methods of each dimension and clarifies the implementation principles and strategies， in order to provide methodological support for high-quality clinical research and the production of high-level evidence-based data in TCM treatment of liver diseases and promote the modernization and internationalization of TCM diagnosis and treatment.
- Liver Diseases /
- Traditional Chinese Medicine Therapy /
- Treatment Outcome

HTML全文

注： LSM，肝硬度值；CLDQ，慢性肝病问卷；SF-36，健康调查简表；PSQI，匹兹堡睡眠量表；VAS，视觉模拟评分；NRS，数字评定量表。

图 1 中医治疗肝纤维化四维疗效评价

Figure 1. Four-Dimensional efficacy evaluation of traditional Chinese medicine in the treatment of hepatic fibrosis

下载: 全尺寸图片幻灯片

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