《2025年美国胃肠病学会临床实践建议更新:肝硬化腹水、容量超负荷及低钠血症的管理》摘译
DOI: 10.12449/JCH260410
An excerpt of AGA clinical practice update on the management of ascites, volume overload, and hyponatremia in cirrhosis: Expert review (2025 edition)
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摘要: 2025年12月,美国胃肠病学会发布了关于肝硬化腹水、容量超负荷及低钠血症管理临床实践更新的专家建议,根据现有证据推荐了13条最佳实践建议,本文对其进行摘译。Abstract: In December 2025, American Gastroenterological Association released the expert review of clinical practice update on the management of ascites, volume overload, and hyponatremia in cirrhosis. The expert review proposes 13 best practice recommendations based on available evidence. This article gives an excerpt of the main recommendations from the expert review.
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Key words:
- Liver Cirrhosis /
- Ascites /
- Hyponatremia /
- Consensus
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表 1 肝硬化相关容量超负荷状况的定义
Table 1. Definitions of volume overload-related conditions cirrhosis
概念 定义 难治性腹水 治疗无效的腹水,或无法通过药物治疗有效预防腹水的早期复发 难治性肝性胸腔积液 对限盐和利尿剂治疗无反应的肝性胸腔积液,需要进行治疗性胸腔穿刺术 难治性低钠血症 尽管接受了最大限度的药物治疗,仍然存在低钠血症 难治性全身性水肿 使用最大剂量的利尿剂后,血容量状况仍无改善,尿钠持续偏低 -
[1] ORMAN ES, FORTUNE BE, JOHN BV, et al. AGA clinical practice update on the management of ascites, volume overload, and hyponatremia in cirrhosis: Expert review[J]. Gastroenterology, 2025, 169( 7): 1547- 1557. DOI: 10.1053/j.gastro.2025.08.029. -

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