中西医结合在慢加急性肝衰竭全病程管理中的特色和优势

高方媛; 冯颖; 王宪波

doi:10.12449/JCH250601

中西医结合在慢加急性肝衰竭全病程管理中的特色和优势

DOI: 10.12449/JCH250601

首都医科大学附属北京地坛医院中西医结合中心，北京 100015

基金项目:

国家自然科学基金 (82474419);

国家自然科学基金 (82474426);

北京市卫生健康委员会-研究型病房卓越临床研究计划 (BRWEP2024W102170107);

北京市医院管理中心创新梦工场经费资助 (202335)

利益冲突声明：本文不存在任何利益冲突。

作者贡献声明：高方媛、冯颖负责文献检索和文章撰写；王宪波负责拟定撰写思路、文章修订及定稿。

详细信息

通信作者:
王宪波， wangxianbo638@163.com （ORCID： 0000-0002-3593-5741）

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出版历程
- 收稿日期: 2025-04-03
- 录用日期: 2025-05-07
- 出版日期: 2025-06-25

Characteristics and advantages of integrated traditional Chinese and Western medicine therapy in whole-course management of acute-on-chronic liver failure

Center of Integrative Medicine，Beijing Ditan Hospital，Capital Medical University，Beijing 100015，China

Research funding:

National Natural Science Foundation of China (82474419);

National Natural Science Foundation of China (82474426);

Beijing Municipal Health Commission-Excellent Clinical Research Program for Research Wards (BRWEP2024W102170107);

Beijing Hospitals Authority Innovation Studio of Young Staff Funding Support (202335)

More Information

Corresponding author: WANG Xianbo， wangxianbo638@163.com （ORCID： 0000-0002-3593-5741）

摘要

摘要: 慢加急性肝衰竭（ACLF）是在慢性肝病基础上，不同诱因导致的急性肝功能恶化，伴随肝脏和/或肝外器官衰竭的复杂临床综合征，短期内病死率极高。随着临床循证医学证据的增多，《慢加急性肝衰竭中医临床诊疗指南》《慢加急性肝衰竭中西医结合诊疗专家共识》和《慢加急性肝衰竭中西医结合诊疗指南》等多部指南和共识相继发布，中西医结合治疗ACLF的方法日趋规范和完善。本文从早期预警和预防、急性期治疗、并发症管理和康复期调护等方面探讨中西医结合在ACLF全病程管理中的特色和优势，以期加强临床医生对中西医治疗策略的认识。
- 慢加急性肝功能衰竭 /
- 中西医结合疗法 /
- 多学科诊疗
Abstract: Acute-on-chronic liver failure （ACLF） is a complex clinical syndrome characterized by acute deterioration of liver function caused by different factors on the basis of chronic liver disease， accompanied by liver failure and/or extrahepatic organ failure， and it often has a high short-term mortality rate. With the increasing evidence of evidence-based medicine， multiple guidelines and consensus statements have been released， such as Guidelines for clinical diagnosis and treatment of acute-on-chronic liver failure in traditional Chinese medicine， Expert consensus on the diagnosis and treatment of acute-on-chronic liver failure with integrated traditional Chinese and Western medicine， and Guidelines for the integrated traditional Chinese and Western medicine diagnosis and treatment of acute-on-chronic liver failure， and integrated traditional Chinese and Western medicine therapies for ACLF have been constantly standardized and perfected. This article explores the characteristics and advantages of integrated traditional Chinese and Western medicine therapy in the whole-course management of ACLF from the aspects of early warning and prevention， treatment in the acute stage， management of complications， and rehabilitation care， in order to enhance the understanding of traditional Chinese and Western medicine treatment strategies among clinicians.
- Acute-On-Chronic Liver Failure /
- Integrated Chinese Traditional and Western Medicine Therapy /
- Multi-Disciplinary Team

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