经内镜逆行胰胆管造影术后消化道穿孔的危险因素及诊疗策略
DOI: 10.12449/JCH250329
利益冲突声明:本文不存在任何利益冲突。
作者贡献声明:赵文玉负责课题设计,拟定写作思路,撰写论文;段亚娇、唐娟负责修改论文;倪静负责文献搜集及分析;傅燕负责指导撰写文章并最后定稿。
Risk factors, diagnosis and treatment of perforation after endoscopic retrograde cholangiopancreatography
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摘要: 经过50年的发展,内镜逆行胰胆管造影(ERCP)目前已经成为胆胰管疾病的首选诊疗手段,但其术后发生胰腺炎、出血、穿孔等主要并发症仍是临床面临的一大难题,其中术后消化道穿孔死亡风险极高。因此,探究ERCP术后穿孔的相关危险因素,及时诊断穿孔,制订精准防治措施至关重要。本文总结了ERCP术后穿孔的相关危险因素及诊疗措施。
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关键词:
- 胰胆管造影术, 内窥镜逆行 /
- 危险因素 /
- 诊断 /
- 治疗学
Abstract: After 50 years of clinical development, endoscopic retrograde cholangiopancreatography (ERCP) has become the preferred method for the clinical diagnosis and treatment of cholangio-pancreatic duct diseases; however, the major postoperative complications of ERCP, such as pancreatitis, hemorrhage, and perforation, are still a difficult issue faced by clinicians, and postoperative perforation is associated with an extremely high risk of death. Therefore, it is very important to explore the risk factors for perforation after ERCP, make a definite diagnosis of perforation in a timely manner, and formulate precise prevention and treatment measures. By reviewing a large number of articles, this article summarizes the influencing factors for perforation after ERCP and related diagnosis and treatment measures.-
Key words:
- Cholangiopancreatography, Endoscopic Retrograde /
- Risk Factors /
- Diagnosis /
- Therapeutics
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[1] GUO SL, YANG X, HU HH, et al. Efficacy and safety of ERCP in minimally invasive treatment for biliary and pancreatic diseases[J/OL]. Chin J Hepatic Surg(Electronic Edition), 2023, 12( 2): 216- 220. DOI: 10.3877/cma.j.issn.2095-3232.2023.02.018.郭世龙, 杨潇, 胡欢欢, 等. ERCP在胆胰疾病微创治疗中的有效性及安全性[J/OL]. 中华肝脏外科手术学电子杂志, 2023, 12( 2): 216- 220. DOI: 10.3877/cma.j.issn.2095-3232.2023.02.018. [2] AK Ç, AYKUT H, PALA EM, et al. Post-ERCP complication analysis of an experienced center[J]. Surg Laparosc Endosc Percutan Tech, 2022, 32( 6): 707- 713. DOI: 10.1097/SLE.0000000000001113. [3] ERCP Group, Chinese Society of Digestive Endoscopology; Group Biliopancreatic, Chinese Association of Gastroenterologist and Hepatologist; National Clinical Research Center for Digestive Diseases. Chinese guidelines for ERCP(2018)[J]. Chin J Int Med, 2018, 57( 11): 772- 801. DOI: 10.3760/cma.j.issn.0578-1426.2018.11.002.中华医学会消化内镜学分会ERCP学组, 中国医师协会消化医师分会胆胰学组, 国家消化系统疾病临床医学研究中心. 中国ERCP指南(2018版)[J]. 中华内科杂志, 2018, 57( 11): 772- 801. DOI: 10.3760/cma.j.issn.0578-1426.2018.11.002. [4] MACHADO NO. Management of duodenal perforation post-endoscopic retrograde cholangiopancreatography. When and whom to operate and what factors determine the outcome? A review article[J]. JOP, 2012, 13( 1): 18- 25. [5] ANDRIULLI A, LOPERFIDO S, NAPOLITANO G, et al. Incidence rates of post-ERCP complications: A systematic survey of prospective studies[J]. Am J Gastroenterol, 2007, 102( 8): 1781- 1788. DOI: 10.1111/j.1572-0241.2007.01279.x. [6] PASPATIS GA, DUMONCEAU JM, BARTHET M, et al. Diagnosis and management of iatrogenic endoscopic perforations: European society of gastrointestinal endoscopy(ESGE) position statement[J]. Endoscopy, 2014, 46( 8): 693- 711. DOI: 10.1055/s-0034-1377531. [7] POLITOVÁ P, DOUDA L, ŠTRINCL L, et al. Perforation of colon sigmoideum as a delayed complication of ERCP[J]. Gastroenterol Hepatol, 2022, 76( 6): 504- 507. DOI: 10.48095/ccgh2022504. [8] ENNS R, ELOUBEIDI MA, MERGENER K, et al. ERCP-related perforations: Risk factors and management[J]. Endoscopy, 2002, 34( 4): 293- 298. DOI: 10.1055/s-2002-23650. [9] KAYASHIMA H, IKEGAMI T, KASAGI Y, et al. Liver parenchyma perforation following endoscopic retrograde cholangiopancreatography[J]. Case Rep Gastroenterol, 2011, 5( 2): 487- 491. DOI: 10.1159/000331135. [10] NASIR UM, AHMED A, PANCHAL D, et al. Endoscopic retrograde cholangiopancreatography leading to pharyngeal perforation[J]. Case Rep Gastroenterol, 2020, 14( 1): 80- 86. DOI: 10.1159/000506182. [11] STAPFER M, SELBY RR, STAIN SC, et al. Management of duodenal perforation after endoscopic retrograde cholangiopancreatography and sphincterotomy[J]. Ann Surg, 2000, 232( 2): 191- 198. DOI: 10.1097/00000658-200008000-00007. [12] CIROCCHI R, KELLY MD, GRIFFITHS EA, et al. A systematic review of the management and outcome of ERCP related duodenal perforations using a standardized classification system[J]. Surgeon, 2017, 15( 6): 379- 387. DOI: 10.1016/j.surge.2017.05.004. [13] COTTON PB, GARROW DA, GALLAGHER J, et al. Risk factors for complications after ERCP: A multivariate analysis of 11, 497 procedures over 12 years[J]. Gastrointest Endosc, 2009, 70( 1): 80- 88. DOI: 10.1016/j.gie.2008.10.039. [14] Endoscopic Surgery Group, Digestive Endoscopy Branch, Chinese Medical Association; Endoscopic Surgery Expert Working Group, Chinese College of Surgeons; Professional Committee of Pancreatic Disease, Chinese Medical Doctor Association. Guideline for the management of complications of duodenal perforation associated with ERCP in China(2023 edition)[J]. Chin J Dig Surg, 2024, 23( 1): 1- 9. DOI: 10.3760/cma.j.cn115610-20231025-00166.中华医学会消化内镜学分会内镜外科学组, 中国医师协会外科医师分会内镜外科专家工作组, 中国医师协会胰腺病专业委员会. 中国ERCP致十二指肠穿孔并发症管理指南(2023版)[J]. 中华消化外科杂志, 2024, 23( 1): 1- 9. DOI: 10.3760/cma.j.cn115610-20231025-00166. [15] KATSINELOS P, LAZARAKI G, CHATZIMAVROUDIS G, et al. Risk factors for therapeutic ERCP-related complications: An analysis of 2, 715 cases performed by a single endoscopist[J]. Ann Gastroenterol, 2014, 27( 1): 65- 72. [16] NAVANEETHAN U, KONJETI R, LOURDUSAMY V, et al. Precut sphincterotomy: Efficacy for ductal access and the risk of adverse events[J]. Gastrointest Endosc, 2015, 81( 4): 924- 931. DOI: 10.1016/j.gie.2014.09.015. [17] LANGERTH A, ISAKSSON B, KARLSON BM, et al. ERCP-related perforations: A population-based study of incidence, mortality, and risk factors[J]. Surg Endosc, 2020, 34( 5): 1939- 1947. DOI: 10.1007/s00464-019-06966-w. [18] WEISER R, PENCOVICH N, MLYNARSKY L, et al. Management of endoscopic retrograde cholangiopancreatography-related perforations: Experience of a tertiary center[J]. Surgery, 2017, 161( 4): 920- 929. DOI: 10.1016/j.surg.2016.10.029. [19] BENSON ME, BYRNE S, BRUST DJ, et al. EUS and ERCP complication rates are not increased in elderly patients[J]. Dig Dis Sci, 2010, 55( 11): 3278- 3283. DOI: 10.1007/s10620-010-1152-2. [20] TAKANO S, FUKASAWA M, SHINDO H, et al. Risk factors for perforation during endoscopic retrograde cholangiopancreatography in post-reconstruction intestinal tract[J]. World J Clin Cases, 2019, 7( 1): 10- 18. DOI: 10.12998/wjcc.v7.i1.10. [21] CHENG CL, LIU NJ, TANG JH, et al. Double-balloon enteroscopy for ERCP in patients with billroth II anatomy: Results of a large series of papillary large-balloon dilation for biliary stone removal[J]. Endosc Int Open, 2015, 3( 3): E216- E222. DOI: 10.1055/s-0034-1391480. [22] LICHTENSTEIN DR. Post-surgical anatomy and ERCP[J]. Tech Gastrointest Endosc, 2007, 9( 2): 114- 124. [23] WU WG, ZHANG WJ, GU J, et al. Retrieval-balloon-assisted enterography for ERCP after Billroth II gastroenterostomy and Braun anastomosis[J]. World J Gastroenterol, 2014, 20( 31): 1 0921- 10926. DOI: 10.3748/wjg.v20.i31.10921. [24] NI JB, ZHU MY, LI K, et al. The feasibility of cap-assisted routine adult colonoscope for therapeutic endoscopic retrograde cholangiopancreatography in patients with Roux-en-Y reconstruction after total gastrectomy[J]. J Dig Dis, 2021, 22( 12): 721- 726. DOI: 10.1111/1751-2980.13069. [25] MU PL, YUE P, LI FW, et al. Does periampullary diverticulum affect ERCP cannulation and post-procedure complications? An up-to-date meta-analysis[J]. Turk J Gastroenterol, 2020, 31( 3): 193- 204. DOI: 10.5152/tjg.2020.19058. [26] KARAAHMET F, KEKILLI M. The presence of periampullary diverticulum increased the complications of endoscopic retrograde cholangiopancreatography[J]. Eur J Gastroenterol Hepatol, 2018, 30( 9): 1009- 1012. DOI: 10.1097/MEG.0000000000001172. [27] JAYARAJ M, MOHAN BP, DHINDSA BS, et al. Periampullary diverticula and ERCP outcomes: A systematic review and meta-analysis[J]. Dig Dis Sci, 2019, 64( 5): 1364- 1376. DOI: 10.1007/s10620-018-5314-y. [28] SFARTI VC, BĂLAN G Jr, AŞ CHIRIAC, et al. Endoscopic retrograde cholangiopancreatography(ERCP) in patients with periampullary diverticula[J]. Rom J Morphol Embryol, 2018, 59( 3): 833- 837. [29] YUE P, WANG ZY, ZHANG LD, et al. Clinical characteristics of choledocholithiasis combined with periampullary diverticulum and influencing factor analysis for difficult cannulation of endoscopic retrograde cholangiopan-creatography: a report of 1 920 cases[J]. Chin J Dig Surg, 2023, 22( 1): 113- 121. DOI: 10.3760/cma.j.cn115610-20221201-00723.岳平, 王震宇, 张雷达, 等. 胆总管结石合并壶腹周围憩室临床特征急行ERCP发生困难插管的影响因素分析(附1 920例报告)[J]. 中华消化外科杂志, 2023, 22( 1): 113- 121. DOI: 10.3760/cma.j.cn115610-20221201-00723. [30] SHI HX, YE YQ, ZHAO HW, et al. A new classification of periampullary diverticulum: Cannulation of papilla on the inner margins of the diverticulum(type IIa) is more challenging[J]. BMC Gastroenterol, 2023, 23( 1): 252. DOI: 10.1186/s12876-023-02862-9. [31] PARK TY, SONG TJ. Recent advances in endoscopic retrograde cholangiopancreatography in billroth II gastrectomy patients: A systematic review[J]. World J Gastroenterol, 2019, 25( 24): 3091- 3107. DOI: 10.3748/wjg.v25.i24.3091. [32] KIM GH, KANG DH, SONG GA, et al. Endoscopic removal of bile-duct stones by using a rotatable papillotome and a large-balloon dilator in patients with a Billroth II gastrectomy(with video)[J]. Gastrointest Endosc, 2008, 67( 7): 1134- 1138. DOI: 10.1016/j.gie.2007.12.016. [33] JANG HW, LEE KJ, JUNG MJ, et al. Endoscopic papillary large balloon dilatation alone is safe and effective for the treatment of difficult choledocholithiasis in cases of billroth II gastrectomy: A single center experience[J]. Dig Dis Sci, 2013, 58( 6): 1737- 1743. DOI: 10.1007/s10620-013-2580-6. [34] NAVANEETHAN U, KONJETI R, VENKATESH PG, et al. Early precut sphincterotomy and the risk of endoscopic retrograde cholangiopancreatography related complications: An updated meta-analysis[J]. World J Gastrointest Endosc, 2014, 6( 5): 200- 208. DOI: 10.4253/wjge.v6.i5.200. [35] MANES G, di GIORGIO P, REPICI A, et al. An analysis of the factors associated with the development of complications in patients undergoing precut sphincterotomy: A prospective, controlled, randomized, multicenter study[J]. Am J Gastroenterol, 2009, 104( 10): 2412- 2417. DOI: 10.1038/ajg.2009.345. [36] PARK SJ, KIM JH, HWANG JC, et al. Factors predictive of adverse events following endoscopic papillary large balloon dilation: Results from a multicenter series[J]. Dig Dis Sci, 2013, 58( 4): 1100- 1109. DOI: 10.1007/s10620-012-2494-8. [37] DUMONCEAU JM, KAPRAL C, AABAKKEN L, et al. ERCP-related adverse events: European society of gastrointestinal endoscopy(ESGE) guideline[J]. Endoscopy, 2020, 52( 2): 127- 149. DOI: 10.1055/a-1075-4080. [38] SHIM CS, KIM JW, LEE TY, et al. Is endoscopic papillary large balloon dilation safe for treating large CBD stones?[J]. Saudi J Gastroenterol, 2016, 22( 4): 251- 259. DOI: 10.4103/1319-3767.187599. [39] YAMAUCHI H, IWAI T, OKUWAKI K, et al. Risk factors for perforation during endoscopic papillary large balloon dilation and bile duct stone removal[J]. Dig Dis Sci, 2022, 67( 5): 1890- 1900. DOI: 10.1007/s10620-021-06974-8. [40] KAMADA H, KOBARA H, YAMANA H, et al. Repeated balloon inflation under low pressure may reduce serious adverse events during endoscopic papillary large balloon dilation[J]. J Hepatobiliary Pancreat Sci, 2022, 29( 5): e33- e35. DOI: 10.1002/jhbp.987. [41] FATIMA J, BARON TH, TOPAZIAN MD, et al. Pancreaticobiliary and duodenal perforations after periampullary endoscopic procedures: Diagnosis and management[J]. Arch Surg, 2007, 142( 5): 448-454; discussion 454-455. DOI: 10.1001/archsurg.142.5.448. [42] IDA BB. A rare clinical presentation of third part duodenal perforation due to post-endoscopic retrograde cholangiopancreatography stent migration on advanced stage peri-ampullary tumor[J]. JGH Open, 2021, 5( 8): 968- 970. DOI: 10.1002/jgh3.12608. [43] TIRELLI F, MIRCO P, FRANSVEA P, et al. Perforation due to biliary stent: Case report and review[J]. Dig Dis Interv, 2021, 5( 4): 324- 330. DOI: 10.1055/s-0041-1733777. [44] GANDHI JA, SHINDE PH, NAGUR BK, et al. Endoscopic retrograde cholangiopancreatography scope-induced duodenojejunal flexure perforation: The world’s first case[J]. J Dig Endosc, 2017, 8( 3): 145- 147. DOI: 10.4103/jde.jde_87_16. [45] BILL JG, SMITH Z, BRANCHECK J, et al. The importance of early recognition in management of ERCP-related perforations[J]. Surg Endosc, 2018, 32( 12): 4841- 4849. DOI: 10.1007/s00464-018-6235-8. [46] BORAZAN E, KONDUK BT. Comparison of early and delayed diagnosis of mortality in ERCP perforations: A high-volume patient experience[J]. Ulus Travma Acil Cerrahi Derg, 2020, 26( 5): 746- 753. DOI: 10.14744/tjtes.2020.61289. [47] CHANDRASEKHARA V, KHASHAB MA, MUTHUSAMY VR, et al. Adverse events associated with ERCP[J]. Gastrointest Endosc, 2017, 85( 1): 32- 47. DOI: 10.1016/j.gie.2016.06.051. [48] MANOHARAN D, SRIVASTAVA DN, GUPTA AK, et al. Complications of endoscopic retrograde cholangiopancreatography: An imaging review[J]. Abdom Radiol(NY), 2019, 44( 6): 2205- 2216. DOI: 10.1007/s00261-019-01953-0. [49] WU HM, DIXON E, MAY GR, et al. Management of perforation after endoscopic retrograde cholangiopancreatography(ERCP): A population-based review[J]. HPB(Oxford), 2006, 8( 5): 393- 399. DOI: 10.1080/13651820600700617. [50] AVGERINOS DV, LLAGUNA OH, LO AY, et al. Management of endoscopic retrograde cholangiopancreatography: Related duodenal perforations[J]. Surg Endosc, 2009, 23( 4): 833- 838. DOI: 10.1007/s00464-008-0157-9. [51] SHIMIZU T, YOSHIOKA M, MATSUSHITA A, et al. Causes and management of endoscopic retrograde cholangiopancreatography-related perforation: A retrospective study[J]. J Nippon Med Sch, 2023, 90( 4): 316- 325. DOI: 10.1272/jnms.JNMS.2023_90-305. [52] GENZLINGER JL, MCPHEE MS, FISHER JK, et al. Significance of retroperitoneal air after endoscopic retrograde cholangiopancreatography with sphincterotomy[J]. Am J Gastroenterol, 1999, 94( 5): 1267- 1270. DOI: 10.1111/j.1572-0241.1999.00996.x. [53] TASAR P, KILICTURGAY SA. Early results of conservative and surgical approach in Endoscopic Retrograde Cholangiopancreatography(ERCP) Perforations Single center experience[J]. Ann Ital Chir, 2023, 94: 367- 374. [54] PASPATIS GA, ARVANITAKIS M, DUMONCEAU JM, et al. Diagnosis and management of iatrogenic endoscopic perforations: European society of gastrointestinal endoscopy(ESGE) position statement-update 2020[J]. Endoscopy, 2020, 52( 9): 792- 810. DOI: 10.1055/a-1222-3191. [55] ODEMIS B, OZTAS E, KUZU UB, et al. Can a fully covered self-expandable metallic stent be used temporarily for the management of duodenal retroperitoneal perforation during ERCP as a part of conservative therapy?[J]. Surg Laparosc Endosc Percutan Tech, 2016, 26( 1): e9- e17. DOI: 10.1097/SLE.0000000000000240. [56] TAVUSBAY C, ALPER E, GÖKOVA M, et al. Management of perforation after endoscopic retrograde cholangiopancreatography[J]. Ulus Travma Acil Cerrahi Derg, 2016, 22( 5): 441- 448. DOI: 10.5505/tjtes.2016.42247. [57] ZHU GY, HU FL, WANG CM. Recent advances in prevention and management of endoscopic retrograde cholangiopancreatography-related duodenal perforation[J]. Wideochir Inne Tech Maloinwazyjne, 2021, 16( 1): 19- 29. DOI: 10.5114/wiitm.2020.101025. [58] JIMÉNEZ CUBEDO E, LÓPEZ MONCLÚS J, LUCENA DE LA POZA JL, et al. Review of duodenal perforations after endoscopic retrograde cholangiopancreatography in Hospital Puerta de Hierro from 1999 to 2014[J]. Rev Esp Enferm Dig, 2018, 110( 8): 515- 519. DOI: 10.17235/reed.2018.5255/2017. [59] KIM K, KIM EB, CHOI YH, et al. Repair of an endoscopic retrograde cholangiopancreatography-related large duodenal perforation using double endoscopic band ligation and endoclipping[J]. Clin Endosc, 2017, 50( 2): 202- 205. DOI: 10.5946/ce.2016.112. [60] MIAO YS, LI YY, CHENG BW, et al. Clinical analysis of 45 cases of perforation were identified during endoscopic retrograde cholangiopancreatography procedure[J]. Front Med(Lausanne), 2022, 9: 1039954. DOI: 10.3389/fmed.2022.1039954. [61] SHI D, YANG JF, LIU YP. Endoscopic treatment of endoscopic retrograde cholangiopancreatography-related duodenal perforations[J]. J Laparoendosc Adv Surg Tech A, 2019, 29( 3): 385- 391. DOI: 10.1089/lap.2018.0617. [62] LEE JH, KEDIA P, STAVROPOULOS SN, et al. AGA clinical practice update on endoscopic management of perforations in gastrointestinal tract: Expert review[J]. Clin Gastroenterol Hepatol, 2021, 19( 11): 2252- 2261. e 2. DOI: 10.1016/j.cgh.2021.06.045. [63] TRINGALI A, CINTOLO M, HASSAN C, et al. Type II-III ERCP-related perforations treated with temporary Fully covered self-expandable stents[J]. Dig Liver Dis, 2017, 49( 10): 1169- 1170. DOI: 10.1016/j.dld.2017.06.005. [64] TRINGALI A, PIZZICANNELLA M, ANDRISANI G, et al. Temporary FC-SEMS for type II ERCP-related perforations: A case series from two referral centers and review of the literature[J]. Scand J Gastroenterol, 2018, 53( 6): 760- 767. DOI: 10.1080/00365521.2018.1458894. [65] BOZBIYIK O, CETIN B, GUMUS T, et al. Fully covered self-expandable metal stent for intraprocedural or late-diagnosed Type-II endoscopic retrograde cholangiopancreatography-related perforations[J]. BMC Gastroenterol, 2022, 22( 1): 385. DOI: 10.1186/s12876-022-02466-9. [66] THEOPISTOS V, THEOCHARIS G, KONSTANTAKIS C, et al. Non-operative management of type 2 ERCP-related retroperitoneal duodenal perforations: A 9-year experience from a single center[J]. Gastroenterology Res, 2018, 11( 3): 207- 212. DOI: 10.14740/gr1007w. [67] SAKAMOTO J, OGURA T, UENO S, et al. Evaluation of exclusive internal endoscopic drainage for complex biloma with transluminal and transpapillary stenting[J]. Endosc Int Open, 2024, 12( 2): e262- e268. DOI: 10.1055/a-2261-3137. [68] ŞENOCAK R, COŞKUN AK, KAYMAK Ş, et al. Successful conservative treatment of type 3 injury(ductal injury) developing after ERCP[J]. Arab J Gastroenterol, 2018, 19( 2): 88- 90. DOI: 10.1016/j.ajg.2018.02.005. -

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