从“六郁”论代谢相关脂肪性肝病的理论与临床实践

童光东; 孙屿昕

doi:10.12449/JCH241004

从“六郁”论代谢相关脂肪性肝病的理论与临床实践

DOI: 10.12449/JCH241004

童光东^{1, 2, , ,},
孙屿昕^{1, 2}

1.
广州中医药大学附属第四临床医学院，广东深圳 230038
2.
南京中医药大学附属深圳市中医院肝病科，广东深圳 230038

基金项目:

深圳市重点实验室计划 (ZDSYS20210623092000002);

广东省基础与应用基础研究基金重点项目 (2022B1515120034);

广东省名中医传承工作室建设项目 (Project of Guaugdong Province TCM 2020.1)

利益冲突声明：本文不存在任何利益冲突。

作者贡献声明：童光东负责拟定文章思路，修改并最终定稿；孙屿昕负责查阅文献，参与论文修改。

详细信息

通信作者:
童光东， tgd755@163.com （ORCID： 0000-0002-8577-574X）

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出版历程
- 收稿日期: 2024-06-08
- 录用日期: 2024-08-01
- 出版日期: 2024-10-25

Theoretical and clinical practice of metabolic associated fatty liver disease based on the theory of “six stagnation diseases”

Guangdong TONG^{1, 2
, ,
,},
Yuxin SUN^{1, 2}

1.
The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine，Shenzhen，Guangdong 230038
2.
Department of Hepatology，Shenzhen Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Chinese Medicine，Shenzhen，Guangdong 230038，China

Research funding:

Shenzhen Key Laboratory Program (ZDSYS20210623092000002);

Key Project of Basic and Applied Basic Research Foundation of Guangdong Province (2022B1515120034);

Project of Guangdong Province Traditional Chinese Medicine Inheritance Studio Construction (Project of Guaugdong Province TCM 2020.1)

More Information

Corresponding author: TONG Guangdong， tgd755@163.com （ORCID： 0000-0002-8577-574X）

摘要

摘要: 代谢相关脂肪性肝病已成为全球第一大肝病，包括单纯性脂肪变性，脂肪性肝炎，纤维化/肝硬化与肝癌，常与代谢综合征相关。其病理复杂，国内尚无新药上市。既往中医认识或从食，或从痰湿，或从湿热，或从肝郁脾虚等论治，但细致分析其疾病的病理过程与中医“六郁”理论相吻合。本文简要介绍了六郁致病理论的源流、导致脂肪肝的“六郁”病变特点，辨治要点与临床实践等，以期通过对代谢相关脂肪肝中医病机的深入认识，促进临床治疗进展。
- 非酒精性脂肪性肝病 /
- 郁证 /
- 中医病因和病机
Abstract: Metabolic associated fatty liver disease （MAFLD） has become the most common liver disease in the world， including simple hepatic steatosis， steatohepatitis， liver fibrosis/cirrhosis， and liver cancer， and it is often associated with metabolic syndrome. MAFLD has complex pathological manifestations， and there are still no new drugs on the market in China. In the past， traditional Chinese medicine often treated this disease from the perspective of food， phlegm-dampness， damp-heat， or liver depression and spleen deficiency， but a detailed analysis showed that the pathological process of the disease was consistent with the theory of “six stagnation diseases” in traditional Chinese medicine. This article briefly introduces the origin of the pathogenic theory of “six stagnation diseases”， the pathological features of the “six stagnation diseases” leading to fatty liver disease， the key points of syndrome differentiation and treatment， and clinical practice， so as to promote clinical treatment through an in-depth understanding of the traditional Chinese medicine pathogenesis of MAFLD.
- Non-alcoholic Fatty Liver Disease /
- Melancholia /
- Etiological Factors and Pathogenesis （TCM）

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参考文献(22)

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