中国乙型肝炎病毒母婴传播防治指南（2024年版）

中国医师协会感染科医师分会; 中华医学会感染病学分会

doi:10.12449/JCH240809

中国乙型肝炎病毒母婴传播防治指南（2024年版）

DOI: 10.12449/JCH240809

基金项目:

陕西省重点研发项目 (2018ZDXM-SF-037);

陕西省重点研发项目 (2024SF-LCZX-14)

利益冲突声明：所有专家在加入本《指南》制定委员会之前签署了利益冲突声明表，不存在与本《指南》相关的利益冲突。

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- 被引次数: 0
出版历程
- 收稿日期: 2024-07-28
- 录用日期: 2024-08-01
- 出版日期: 2024-08-25

Chinese practice guideline for the prevention and treatment of mother-to-child transmission of hepatitis B virus （version 2024）

Research funding:

Key Research and Development Projects of Shaanxi Province (2018ZDXM-SF-037);

Key Research and Development Projects of Shaanxi Province (2024SF-LCZX-14)

摘要

摘要: 中华医学会感染病学分会制定的《中国乙型肝炎病毒母婴传播防治指南（2019年版）》（简称2019版《指南》）对国内乙型肝炎病毒母婴传播阻断流程的规范化起到了良好的指导作用。临床实践指南和共识需要随新研究证据的出现，及时更新以更好地指导临床实践和研究。中国医师协会感染科医师分会和中华医学会感染病学分会联合多学科专家，基于国内外最新研究进展，结合临床实践，对2019版《指南》进行了更新和补充，为临床医师和妇幼保健工作人员提供指导和参考。
- 乙型肝炎病毒 /
- 母婴传播 /
- 预防 /
- 治疗 /
- 指南 /
- 更新
Abstract: The 2019 Chinese practice guideline for the prevention and treatment of mother-to-child transmission of hepatitis B virus developed by Chinese Society of Infectious Diseases， Chinese Medical Association， has shown a good guiding effect in standardizing the process for blocking the mother-to-child transmission of hepatitis B virus in China. Clinical practice guidelines and consensus statements require timely updates based on new research evidence， in order to better guide clinical practice and research. Chinese Physician Association for Infectious Diseases， Chinese Medical Doctor Association， and Chinese Society of Infectious Diseases， Chinese Medical Association， cooperated with multidisciplinary experts and performed updates and supplementations to the above guideline， in order to provide guidance and a reference for clinical physicians and medical staff engaged in maternal and child health care.
- Hepatitis B Virus /
- Mother-to-Child Transmission /
- Prevention /
- Treatment /
- Guidelines /
- Update

HTML全文

图 1 HBV母婴传播防治流程

注： HBsAg，乙型肝炎表面抗原；CHB，慢性乙型肝炎；TDF，富马酸替诺福韦二吡呋酯；TAF，富马酸丙酚替诺福韦；HBeAg，乙型肝炎e抗原；抗-HBs，乙型肝炎表面抗体。*综合评估，包括肝生化学、HBV血清病毒学标志物、HBV DNA和影像学检查等；#停药时间，产后立即～产后3个月停药肝生化指标异常率无差别。

Figure 1. Flow chart of prevention and treatment of mother-to-child transmission of HBV

下载: 全尺寸图片幻灯片

表 1 GRADE证据质量与推荐强度分级

Table 1. GRADE evidence quality and recommendation strength classification

分级	具体描述
证据质量分级
高（A）	非常有把握观察值接近真实值
中（B）	对观察值有中等把握：观察值有可能接近真实值，但也有可能差别很大
低（C）	对观察值的把握有限：观察值可能与真实值有很大差别
极低（D）	对观察值几乎没有把握：观察值与真实值可能有极大差别
推荐强度分级
强（1）	明确显示干预措施利大于弊或弊大于利
弱（2）	利弊不确定或无论质量高低的证据均显示利弊相当

下载: 导出CSV

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