金属离子代谢： 慢性肝病中医药防治新思路

郭新华; 王佳慧; 段雪琳; 彭岳; 赵铁建; 郑洋; 赵斌

doi:10.12449/JCH240732

金属离子代谢：慢性肝病中医药防治新思路

DOI: 10.12449/JCH240732

郭新华^1a,
王佳慧²,
段雪琳^1b,
彭岳^1c,
赵铁建^1c,
郑洋²,
赵斌^2, , ,

1a.
广西中医药大学瑞康临床医学院，南宁 530222
1b.
广西中医药大学壮医药学院，南宁 530222
1c.
广西中医药大学基础医学院，南宁 530222
2.
广西中医药大学赛恩斯新医药学院，南宁 530222

基金项目:

国家自然科学基金 (82204755);

国家自然科学基金 (81960751);

广西自然青年基金 (2023GXNSFBA026274);

广西自然青年基金 (2024GXNSFAA010235);

广西中医药大学青年基金 (2022QN008);

广西中医药大学赛恩斯新医药学院科研项目 (2023MS008);

广西中医药大学赛恩斯新医药学院科研项目 (2022CX004)

利益冲突声明：本文不存在任何利益冲突。

作者贡献声明：郭新华、王佳慧负责课题设计，资料分析，撰写论文；段雪琳、彭岳、赵铁建参与查阅文献，整理数据，修改论文；郑洋、赵斌负责拟定写作思路，指导撰写文章并最后定稿。

详细信息

通信作者:
赵斌， yixue960@163.com （ORCID： 0009-0009-9429-8381）

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- 文章访问数: 135
- HTML全文浏览量: 79
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- 被引次数: 0
出版历程
- 收稿日期: 2024-02-07
- 录用日期: 2024-04-01
- 出版日期: 2024-07-25

Metal ion metabolism： New ideas for the traditional Chinese medicine prevention and treatment of chronic liver disease

1a.
Ruikang Clinical Medical College Guangxi University of Chinese Medicine，Nanning 530222，China
1b.
College of Zhuang Medicine Guangxi University of Chinese Medicine，Nanning 530222，China
1c.
College of Basic Medical Sciences Guangxi University of Chinese Medicine，Nanning 530222，China
2.
Faculty of Chinese Medicine Science Guangxi University of Chinese Medicine，Nanning 530222，China

Research funding:

National Natural Science Foundation of China (82204755);

National Natural Science Foundation of China (81960751);

Guangxi Natural Youth Foundation (2023GXNSFBA026274);

Guangxi Natural Youth Foundation (2024GXNSFAA010235);

Guangxi University of Traditional Chinese Medicine Youth Foundation (2022QN008);

Research Project of Sains New Medical College, Guangxi University of Traditional Chinese Medicine (2023MS008);

Research Project of Sains New Medical College, Guangxi University of Traditional Chinese Medicine (2022CX004)

More Information

Corresponding author: ZHAO Bin， yixue960@163.com （ORCID： 0009-0009-9429-8381）

摘要

摘要: 慢性肝病具有较高的发病率，给社会和家庭带来沉重负担。研究发现金属离子代谢与慢性肝病密切相关，部分中草药可以通过调控金属离子代谢发挥防治慢性肝病的作用。目前用于治疗慢性肝病的合成药物疗效并不理想，因此多种中草药被用于慢性肝病的补充和替代疗法。本文介绍了金属离子代谢在慢性肝病中的作用和中草药及其活性成分对慢性肝病的调控作用，分析表明金属离子代谢有望为慢性肝病的研究提供新思路，为临床慢性肝病的治疗提供理论依据。对于金属离子代谢防治慢性肝病，未来还需要更多前瞻性临床研究数据，为慢性肝病患者提供有效、安全的治疗方案。
- 肝疾病 /
- 金属离子 /
- 中草药
Abstract: Chronic liver disease （CLD） tends to have a high incidence rate and impose a serious burden on society and families. Studies have shown that metal ion metabolism is closely associated with CLD， and some Chinese herbal medicines can play a role in the prevention and treatment of CLD by regulating metal ion metabolism. At present， the synthetic drugs currently used for the treatment of CLD fail to achieve a satisfactory effect， and therefore， a variety of Chinese herbal medicines are being used as supplementary and alternative therapies for CLD. This article introduces the role of metal ion metabolism in CLD and the regulatory effect of Chinese herbal medicines and their active components on CLD， and the analysis shows that metal ion metabolism is expected to provide new ideas for the research on CLD and a theoretical basis for the clinical treatment of CLD. For the role of metal ion metabolism in the treatment of CLD， more prospective clinical study data are needed in the future to provide effective and safe treatment regimens for patients with CLD.
- Liver Diseases /
- Metal Ions /
- Drugs， Chinese Herbal

HTML全文

图 1 金属离子代谢在慢性肝病中的作用

Figure 1. The role of metal ion metabolism in chronic liver disease

下载: 全尺寸图片幻灯片

图 2 中医药通过影响金属离子代谢调控慢性肝病

Figure 2. Traditional Chinese medicine regulates chronic liver disease by affecting metal ion metabolism

下载: 全尺寸图片幻灯片

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