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T淋巴细胞免疫球蛋白黏蛋白分子3在肝脏疾病发生发展中的作用

袁诗雨 杨焕焕 唐映梅

引用本文:
Citation:

T淋巴细胞免疫球蛋白黏蛋白分子3在肝脏疾病发生发展中的作用

DOI: 10.12449/JCH240632
基金项目: 

国家自然科学基金 (82360108);

云南省医学领军人才项目 (L-2019013);

云南万人计划 (YNWR-MY-2018-028);

中国联合肝脏健康促进中心-戊型肝炎防治专项基金 (CLH2023-F-HEV-08);

云南省科技人才与平台计划 (Academician Expert Workstation 202305AF150065);

昆明医科大学第二附属医院临床研究项目 (2020ynlc010);

昆明医科大学第二附属医院临床研究项目 (ynIIT2021017)

利益冲突声明:本文不存在任何利益冲突。
作者贡献声明:袁诗雨负责文献阅读分析,拟定写作思路,撰写论文;杨焕焕参与修改论文;唐映梅负责指导撰写文章并最后定稿。
详细信息
    通信作者:

    唐映梅, tangyingmei_med@kmmu.edu.cn (ORCID: 0000-0002-0731-4198)

Role of T-cell immunoglobulin and mucin domain-containing molecule 3 in the development and progression of liver diseases

Research funding: 

National Natural Science Foundation of China (82360108);

Yunnan Medical Leading Talent Project (L-2019013);

Yunnan Ten Thousand Talents Project (YNWR-MY-2018-028);

China United Liver Health Promotion Center - Special Fund for Hepatitis E Prevention and Treatment (CLH2023-F-HEV-08);

Yunnan Provincial Science and Technology Talent and Platform Program (Academician Expert Workstation 202305AF150065);

Clinical Research Project of the Second Affiliated Hospital of Kunming Medical University (2020ynlc010);

Clinical Research Project of the Second Affiliated Hospital of Kunming Medical University (ynIIT2021017)

More Information
  • 摘要: T淋巴细胞免疫球蛋白黏蛋白分子3(Tim-3)是Tim家族中的一员,为近年来研究热点。Tim-3作为负性调节因子通过与不同配体结合发挥不同效应。多种免疫细胞可表达Tim-3,如自然杀伤细胞、树突状细胞和单核细胞,Tim-3对这些免疫细胞功能具有调控作用。近年来大量研究显示Tim-3与肝脏疾病发生发展有着密切关系。本文回顾了近几年Tim-3在不同肝脏疾病及不同细胞中作用及机制的研究,旨在为肝脏疾病的临床诊疗提供更丰富的视角及思路。

     

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  • 收稿日期:  2023-09-06
  • 录用日期:  2023-10-10
  • 出版日期:  2024-06-25
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