胰源性糖尿病的发病机制与诊治进展

王希望; 金晶晶; 王莹; 王晨晓; 张永华; 顾亚娇; 王晓

doi:10.12449/JCH240532

胰源性糖尿病的发病机制与诊治进展

DOI: 10.12449/JCH240532

1.
河南中医药大学第一临床医学院，郑州 450000
2.
河南中医药大学第一附属医院脾胃肝胆科，郑州 450000

基金项目:

河南省特色骨干学科中医学学科建设项目 (STG-ZYX02-202116);

河南省中医药科学研究专项课题 (2019JDZX2050)

利益冲突声明：本文不存在任何利益冲突。

作者贡献声明：王希望、王晨晓、张永华对研究思路或设计有关键贡献，参与研究数据的获取、分析、解释工作；金晶晶、王莹参与撰写及修改文章；王晓、顾亚娇对文章关键内容进行指导与修改。

详细信息

通信作者:
王晓， wangxiao1113@126.com （ORCID： 0000-0002-4676-2487）

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出版历程
- 收稿日期: 2023-08-02
- 录用日期: 2023-09-14
- 出版日期: 2024-05-25

Pathogenesis, diagnosis, and treatment of pancreatogenic diabetes

1.
The First Clinical Medical College of Henan University of Chinese Medicine，Zhengzhou 450000，China
2.
Spleen，Stomach and Hepatobiliary Department，The First Affiliated Hospital of Henan University of Chinese Medicine，Zhengzhou 450000，China

Research funding:

Henan Characteristic Backbone Discipline Construction Project of Traditional Chinese Medicine (STG-ZYX02-202116);

Special Project of Traditional Chinese Medicine in Henan Province (2019JDZX2050)

More Information

Corresponding author: WANG Xiao， wangxiao1113@126.com （ORCID： 0000-0002-4676-2487）

摘要

摘要: 胰源性糖尿病是一种继发于胰腺外分泌疾病的糖尿病，2014年被美国糖尿病学会正式提出，其最常见的病因是慢性胰腺炎，其次是胰腺癌。目前该病的临床误诊率极高，且胰源性糖尿病患者相较于2型糖尿病患者有更高的死亡和再入院风险。因此，充分了解、并早期正确识别及诊断胰源型糖尿病，对降低该病的致残率与病死率具有重要意义。本文全面总结了继发于胰腺炎及胰腺癌的胰源性糖尿病的可能发病机制、诊治与管理等方面的研究进展。
- 胰腺疾病 /
- 糖尿病 /
- 胰岛素 /
- 诊断 /
- 治疗学
Abstract: Pancreatogenic diabetes is a type of diabetes mellitus secondary to exocrine pancreatic disease， and it was officially proposed by the American Diabetes Association in 2014， with chronic pancreatitis as the most common etiology， followed by pancreatic cancer. At present， the misdiagnosis rate of this disease is extremely high， and patients with pancreatogenic diabetes have a higher risk of death and readmission than patients with type 2 diabetes. Therefore， it is of great significance to fully understand， correctly identify， and diagnose pancreatogenic diabetes in the early state， so as to reduce the disability rate and mortality rate of this disease. This article reviews the advances in the possible pathogenesis， diagnosis， treatment， and management of pancreatic diabetes secondary to pancreatitis and pancreatic cancer.
- Pancreatic Diseases /
- Diabetes Mellitus /
- Insulin /
- Diagnosis /
- Therapeutics

HTML全文

图 1 巨噬细胞促进胰腺纤维化的作用机制

Figure 1. Mechanism of macrophages promoting pancreatic fibrosis

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