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Expert consensus on integrated traditional Chinese and Western medicine diagnosis and treatment of chronic hepatitis B
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摘要: 慢性乙型肝炎（CHB）仍是我国重大公共卫生问题，未经有效控制可进一步发展为肝硬化、肝癌，带来巨大社会经济负担。目前西医抗病毒治疗是其主要治疗方式，中西医结合治疗是我国CHB的特色治疗手段，两者优势互补可提高临床疗效。为推广中西医结合协同诊疗理念，促进CHB中西医结合诊疗技术发展，建立规范化、标准化疾病诊断和治疗方案，中国医师协会中西医结合医师分会肝病学专家委员会牵头成立共识专家组，讨论并制定《慢性乙型肝炎中西医结合诊疗专家共识》，从CHB的流行病学、发病机制与病因病机、中西医结合诊断与辨证分型、中西医结合治疗四个方面阐述中西医结合协同诊疗理念并提供推荐意见，期望改善CHB患者预后，提高生活质量。Abstract: Chronic hepatitis B （CHB） is still a major public health issue in China， and without effective control， it can further progress to liver cirrhosis and liver cancer， bringing huge social and economic burdens. At present， antiviral therapy is the main treatment method for CHB， and integrated traditional Chinese and Western medicine therapy is the characteristic treatment method for CHB in China and can improve clinical efficacy by complementing each other’s advantages. In order to promote the concept integrated traditional Chinese and Western medicine collaborative diagnosis and treatment， facilitate the development of integrated traditional Chinese and Western medicine diagnosis and treatment techniques for CHB， and establish standardized disease diagnosis and treatment regimens， Expert Committee on Hepatology in Doctor Society of Integrative Medicine， Chinese Medical Doctor Association， established a consensus expert group to discuss and formulate Expert consensus on integrated traditional Chinese and Western medicine diagnosis and treatment of chronic hepatitis B， which elaborated on the concept of integrated traditional Chinese and Western medicine collaborative diagnosis and treatment from the four aspects of CHB epidemiology， pathogenesis and etiology， integrated traditional Chinese and Western medicine diagnosis and syndrome differentiation， and integrated traditional Chinese and Western medicine therapy and proposed related recommendations， in order to improve the prognosis and quality of life of CHB patients.
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表 1 推荐意见的证据等级和推荐强度
Table 1. Evidence grade and strength of recommendation of recommendations
级别 详细说明 证据等级 Ⅰ 大样本（≥100例），随机对照研究，结果清晰，假阳性或假阴性的错误很低 Ⅱ 小样本（<100例），随机对照研究，结果不确定，假阳性和/或假阴性的错误较高 Ⅲ 非随机，同期对照研究和基于古代文献的专家共识 Ⅳ 非随机，历史对照和当代专家共识 Ⅴ 病例报道，非对照研究和专家意见 推荐强度 A 至少有2项Ⅰ级研究结果支持 B 仅有1项Ⅰ级研究结果支持 C 仅有Ⅱ级研究结果支持 D 至少有1项Ⅲ级研究结果支持 E 仅有Ⅳ级或Ⅴ级研究结果支持 
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