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Drug resistance to nucleoside and nucleotide analogs in chronic hepatitis B and its management
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摘要:
<正>在核苷和核苷酸类药物（nucleoside and nucleotide ana-logs,NAs）治疗慢性乙型肝炎过程中,耐药是一个极为重要的问题。与未发生耐药的患者比较,耐药不仅可导致疾病进一步进展,并可增加发生肝功能失代偿和肝细胞癌（HCC）的风险;还会加大后续治疗的难度,增加长期治疗的医疗成本。
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Key words:
- hepatitis B /
- chronic /
- drug resistance /
- nucleoside and nucleotide analogs
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