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Current perspectives on prevention and treatment of small-for-size syndrome in living donor liver transplantation
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摘要:
活体肝移植是治疗终末期肝病最有效的手段,但小肝综合征是成人活体肝移植术后一种发生率和病死率都较高的临床并发症,是制约成人间活体肝移植的主要原因之一。目前,如何有效防治小肝综合征已成为肝移植领域的研究热点。本篇就活体肝移植后小肝综合征的病理生理、危险因素及防治策略的最新进展作一简要综述。
Abstract:Living donor liver transplantation (LDLT) is the most effective method available for treating patients with end-stage liver disease; however, the small-for-size syndrome (SFSS) is one of the clinical complications with the highest rates of morbidity and mortality after adult living donor liver transplantation. SFSS remains one of the principal factors restricting the progress of liver transplantation. Recently, extensive research efforts have focused on developing methods to prevent and treat SFSS. This article reviews the current progress that has been made in understanding SFSS pathophysiology, its risk factors, and methods of prevention and treatment.
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